Lack of association of PTPN1 gene polymorphisms with type 2 diabetes in south Indians
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  • 作者:DHANASEKARAN BODHINI (1)
    VENKATESAN RADHA (1)
    SAURABH GHOSH (2)
    PARTHA P. MAJUMDER (2)
    VISWANATHAN MOHAN (1)
  • 关键词:PTPN1 gene ; type 2 diabetes ; PTPN1 polymorphisms ; Asian Indians
  • 刊名:Journal of Genetics
  • 出版年:2011
  • 出版时间:August 2011
  • 年:2011
  • 卷:90
  • 期:2
  • 页码:323-326
  • 全文大小:480KB
  • 参考文献:1. Alberti M. M. and Zimmet P. Z. 1998 Definition diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus, provisional report of a WHO consultation. / Diabetic Med. 15, 539鈥?53. CrossRef
    2. Barrett J. C., Fry B., Maller J. and Daly M. J. 2005 Haploview: analysis and visualization of LD and haplotype maps. / Bioinformatics 21, 263鈥?65. CrossRef
    3. Bento J. L., Palmer N. D., Mychaleckyj J. C., Lange L. A., Langefeld C. D., Rich S. S. / et al. 2004 Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. / Diabetes 53, 3007鈥?012. CrossRef
    4. Deepa M., Pradeepa R., Rema M., Anjana M., Deepa R., Shanthirani S. / et al. 2003 The Chennai Urban Rural Epidemiology Study (CURES)- study design and methodology (Urban component) (CURES1). / J. Assoc. Phys. India 51, 863鈥?70.
    5. Echwald S. M., Bach H., Vestergaard H., Richelesen B., Kristensen K., Drivsholm T. / et al. 2002 A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phoshorylation of PTP-1B / in vitro. / Diabetes 51, 1鈥?. CrossRef
    6. Florez J. C., Agapkis C. M., Burtt N. P., Sun M., Almgren P., Rastam L. / et al. 2005 Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people. / Diabetes 54, 1884鈥?891. CrossRef
    7. Majumdar P. and Majumder P. P. 1999 HAPLOPOP: A computer program package to estimate haplotype frequencies from genotype frequencies via the EM algorithm. / AHGU Technical Report 1/99, Indian Statistical Institute, Calcutta, India.
    8. Matthews D. R., Hosker J. P., Rudenski A. S., Naylor B. A., Treacher D. F. and Turner R. C. 1985 Homeostasis model assessment: insulin resistance and / 尾 cell function from fasting plasma glucose and insulin concentrations in man. / Diabetologia 28, 412鈥?19. CrossRef
    9. Mok A., Cao H., Zinman B., Hanley A. J., Harris S. B., Kennedy B. P. / et al. 2002 A Single nucleotide polymorphism in protein tyrosine phosphatase PTP-1B is associated with protection from diabetes or impaired glucose tolerance. / J. Clin. Endocrinol. Metab. 87, 724鈥?27. CrossRef
    10. Palmer N. D., Bento J. L., Mychaleckyj J. C., Langefeld C. D., Campbell J. K., Norris J. M. / et al. 2004 Insulin resistance atherosclerosis study (IRAS) family study. Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. The insulin resistance atherosclerosis (IRAS) family study. / Diabetes 53, 3013鈥?019. CrossRef
    11. Radha V. and Mohan V. 2007 Genetic predisposition to type 2 diabetes among Asian Indians. / Indian J. Med. Res. 125, 259鈥?74.
    12. Traurig M., Hanson R. L., Kobes S., Bogardus C. and Baier L. J. 2007 Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians. / Diabetologia 50, 985鈥?89. CrossRef
    13. Wanic K., Malecki M. T., Klupat J. H., Warram J. H., Sieradzki J. and Krolewski A. S. 2007 Lack of association between polymorphisms in the gene encoding protein tyrosine phosphatase 1B (PTPN1) and risk of type 2 diabetes. / Diabetic Med. 24, 650鈥?55. CrossRef
  • 作者单位:DHANASEKARAN BODHINI (1)
    VENKATESAN RADHA (1)
    SAURABH GHOSH (2)
    PARTHA P. MAJUMDER (2)
    VISWANATHAN MOHAN (1)

    1. Madras Diabetes Research Foundation, ICMR Advanced Centre for Genomics of Type 2 Diabetes and Dr Mohan鈥檚 Diabetes Specialities Centre, Gopalapuram, Chennai 600 086, India
    2. Human Genetics Unit, Indian Statistical Institute, Kolkata, 700 108, India
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