Frontotemporale Demenzen
详细信息 查看全文
- 作者：Prof. Dr. K. Witt (1)
G. Deuschl (1)
T. Bartsch (1) - 关键词：Frontotemporale Demenz ; Prim盲r progressive Aphasien ; TAR ; DNA ; bindendes Protein 43 ; Diagnosekriterien ; Therapie ; Frontotemporal dementia ; Primary progressive aphasias ; TAR ; DNA binding protein 43 ; Diagnostic criteria ; Treatment
- 刊名：Der Nervenarzt
- 出版年：2013
- 出版时间：January 2013
- 年：2013
- 卷：84
- 期：1
- 页码：20-32
- 全文大小：849KB
- 参考文献：1. S3 Leitlinie 鈥濪emenzen鈥?(2009) http://www.dgn.org/images/stories/dgn/pdf/s3_leitlinie_demenzen.pdf
2. Ahmad ST, Sweeney ST, Lee JA et al (2009) Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. Proc Natl Acad Sci U S A 106:12168鈥?2173 CrossRef
3. Allman JM, Watson KK, Tetreault NA, Hakeem AY (2005) Intuition and autism: a possible role for Von Economo neurons. Trends Cogn Sci 9:367鈥?73 CrossRef
4. Bak TH (2007) Overlap Syndromes. In: Hodges JR (Hrsg) Frontotemporal dementia syndromes. Cambridge Univ Press, Cambridge, S聽80鈥?01
5. Baker M, Mackenzie IR, Pickering-Brown SM et al (2006) Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 442:916鈥?19 CrossRef
6. Binetti G, Locascio JJ, Corkin S et al (2000) Differences between Pick disease and Alzheimer disease in clinical appearance and rate of cognitive decline. Arch Neurol 57:225鈥?32 CrossRef
7. Blundo C, Marin D, Ricci M (2011) Vitamin B12 deficiency associated with symptoms of frontotemporal dementia. Neurol Sci 32:101鈥?05 CrossRef
8. Bozeat S, Gregory CA, Ralph MA, Hodges JR (2000) Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer鈥檚 disease? J Neurol Neurosurg Psychiatry 69:178鈥?86 CrossRef
9. Burrell JR, Kiernan MC, Vucic S, Hodges JR (2011) Motor Neuron dysfunction in frontotemporal dementia. Brain. DOI 10.1093/brain/awr195
10. Caselli RJ, Yaari R (2007) Medical management of frontotemporal dementia. Am J Alzheimers Dis Other Demen 22:489鈥?98 CrossRef
11. Cohen L, Benoit N, Van Eeckhout P et al (1993) Pure progressive aphemia. J Neurol Neurosurg Psychiatry 56:923鈥?24 CrossRef
12. Cummings JL, Mega M, Gray K et al (1994) The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 44:2308鈥?314 CrossRef
13. Davies RR, Kipps CM, Mitchell J et al (2006) Progression in frontotemporal dementia: identifying a benign behavioral variant by magnetic resonance imaging. Arch Neurol 63:1627鈥?631 CrossRef
14. Diehl-Schmid J, Grimmer T, Drzezga A et al (2007) Decline of cerebral glucose metabolism in frontotemporal dementia: a longitudinal 18F-FDG-PET-study. Neurobiol Aging 28:42鈥?0 CrossRef
15. Diehl-Schmid J, Knels C, Danek A (2009) Chronic progressive aphasia. Nervenarzt 80:1452鈥?461 CrossRef
16. Diehl-Schmid J, Pohl C, Perneczky R et al (2006) Behavioral disturbances in the course of frontotemporal dementia. Dement Geriatr Cogn Disord 22:352鈥?57 CrossRef
17. Dubois B, Slachevsky A, Pillon B et al (2005) 鈥濧pplause sign鈥?helps to discriminate PSP from FTD and PD. Neurology 64:2132鈥?133 CrossRef
18. Ernst J, Krapp S, Schuster T et al (2010) Car driving ability of patients with frontotemporal lobar degeneration and Alzheimer鈥檚 disease. Nervenarzt 81:79鈥?5 CrossRef
19. Fellgiebel A, Muller MJ, Hiemke C et al (2007) Clinical improvement in a case of frontotemporal dementia under aripiprazole treatment corresponds to partial recovery of disturbed frontal glucose metabolism. World J Biol Psychiatry 8:123鈥?26 CrossRef
20. Folstein MF, Folstein SE, McHugh PR (1975) 鈥濵ini-mental state鈥? a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189鈥?98 CrossRef
21. Frings L, Mader I, Landwehrmeyer BG et al (2011) Quantifying change in individual subjects affected by frontotemporal lobar degeneration using automated longitudinal MRI volumetry. Hum Brain Mapp (in press)
22. Frisoni GB, Pizzolato G, Bianchetti A et al (1994) Single photon emission computed tomography with [99Tc]-HM-PAO and [123I]-IBZM in Alzheimer鈥檚 disease and dementia of frontal type: preliminary results. Acta Neurol Scand 89:199鈥?03 CrossRef
23. Frolich L (2010) S3 guidelines on dementia. Symptomatic therapy of dementia. Nervenarzt 81:796鈥?04 CrossRef
24. Galton CJ, Gomez-Anson B, Antoun N et al (2001) Temporal lobe rating scale: application to Alzheimer鈥檚 disease and frontotemporal dementia. J Neurol Neurosurg Psychiatry 70:165鈥?73 CrossRef
25. Galton CJ, Patterson K, Xuereb JH, Hodges JR (2000) Atypical and typical presentations of Alzheimer鈥檚 disease: a clinical, neuropsychological, neuroimaging and pathological study of 13 cases. Brain 123:484鈥?98 CrossRef
26. Gorno-Tempini ML, Brambati SM, Ginex V et al (2008) The logopenic/phonological variant of primary progressive aphasia. Neurology 71:1227鈥?234 CrossRef
27. Gorno-Tempini ML, Dronkers NF, Rankin KP et al (2004) Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol 55:335鈥?46 CrossRef
28. Gorno-Tempini ML, Hillis AE, Weintraub S et al (2011) Classification of primary progressive aphasia and its variants. Neurology 76:1006鈥?014 CrossRef
29. Gotz J, Ittner A, Ittner LM (2011) Tau-targeted treatment strategies in Alzheimer鈥檚 disease. Br J Pharmacol (in press)
30. Green J, Morris JC, Sandson J et al (1990) Progressive aphasia: a precursor of global dementia? Neurology 40:423鈥?29 CrossRef
31. Harvey RJ, Skelton-Robinson M, Rossor MN (2003) The prevalence and causes of dementia in people under the age of 65 years. J Neurol Neurosurg Psychiatry 74:1206鈥?209 CrossRef
32. Hodges JR (2007) Overview of frontotemporal dementia. In: Hodges JR (Hrsg) Frontotemporals dementia syndromes. Cambridge Univ Press, Cambridge, S聽1鈥?4
33. Hodges JR, Davies R, Xuereb J et al (2003) Survival in frontotemporal dementia. Neurology 61:349鈥?54 CrossRef
34. Hutton M, Lendon CL, Rizzu P et al (1998) Association of missense and 5鈥?splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393:702鈥?05 CrossRef
35. Imamura T, Hirono N, Hashimoto M et al (1999) Clinical diagnosis of dementia with Lewy bodies in a Japanese dementia registry. Dement Geriatr Cogn Disord 10:210鈥?16 CrossRef
36. Isaacs AM, Johannsen P, Holm I, Nielsen JE (2011) Frontotemporal dementia caused by CHMP2B mutations. Curr Alzheimer Res 8:246鈥?51 CrossRef
37. Jeong Y, Park KC, Cho SS et al (2005) Pattern of glucose hypometabolism in frontotemporal dementia with motor neuron disease. Neurology 64:734鈥?36 CrossRef
38. Johnson JK, Diehl J, Mendez MF et al (2005) Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol 62:925鈥?30 CrossRef
39. Josephs KA (2008) Frontotemporal dementia and related disorders: deciphering the enigma. Ann Neurol 64:4鈥?4 CrossRef
40. Josephs KA, Duffy JR, Strand EA et al (2006) Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. Brain 129:1385鈥?398 CrossRef
41. Kipps CM, Knibb JA, Hodges JR (2007) Clinical presentations fo frontotemporal dementia. In: Hodges JR (Hrsg) Frontotemporal dementia Syndromes. Cambridge Univ Press, Cambridge, S聽38鈥?9
42. Kitagaki H, Mori E, Yamaji S et al (1998) Frontotemporal dementia and Alzheimer disease: evaluation of cortical atrophy with automated hemispheric surface display generated with MR images. Radiology 208:431鈥?39
43. Lebert F, Stekke W, Hasenbroekx C, Pasquier F (2004) Frontotemporal dementia: a randomised, controlled trial with trazodone. Dement Geriatr Cogn Disord 17:355鈥?59 CrossRef
44. Likeman M, Anderson VM, Stevens JM et al (2005) Visual assessment of atrophy on magnetic resonance imaging in the diagnosis of pathologically confirmed young-onset dementias. Arch Neurol 62:1410鈥?415 CrossRef
45. Lindau M, Jelic V, Johansson SE et al (2003) Quantitative EEG abnormalities and cognitive dysfunctions in frontotemporal dementia and Alzheimer鈥檚 disease. Dement Geriatr Cogn Disord 15:106鈥?14 CrossRef
46. Mendez MF (2009) Frontotemporal dementia: therapeutic interventions. Front Neurol Neurosci 24:168鈥?78 CrossRef
47. Mendez MF, Perryman KM (2002) Neuropsychiatric features of frontotemporal dementia: evaluation of consensus criteria and review. J Neuropsychiatry Clin Neurosci 14:424鈥?29 CrossRef
48. Mendez MF, Shapira JS, McMurtray A, Licht E (2007) Preliminary findings: behavioral worsening on donepezil in patients with frontotemporal dementia. Am J Geriatr Psychiatry 15:84鈥?7 CrossRef
49. Mesulam MM (1982) Slowly progressive aphasia without generalized dementia. Ann Neurol 11:592鈥?98 CrossRef
50. Moretti R, Torre P, Antonello RM et al (2004) Rivastigmine in frontotemporal dementia: an open-label study. Drugs Aging 21:931鈥?37 CrossRef
51. Mummery CJ, Patterson K, Price CJ et al (2000) A voxel-based morphometry study of semantic dementia: relationship between temporal lobe atrophy and semantic memory. Ann Neurol 47:36鈥?5 CrossRef
52. Neary D, Snowden JS, Gustafson L et al (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546鈥?554 CrossRef
53. Nestor PJ, Graham NL, Fryer TD et al (2003) Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula. Brain 126:2406鈥?418 CrossRef
54. Neumann M, Kretzschmar HA (2008) Molecular neuropathology of Non-Alzheimer dementia. Pathologe 29:434鈥?41 CrossRef
55. Neumann M, Sampathu DM, Kwong LK et al (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314:130鈥?33 CrossRef
56. Nimchinsky EA, Gilissen E, Allman JM et al (1999) A neuronal morphologic type unique to humans and great apes. Proc Natl Acad Sci U S A 96:5268鈥?273 CrossRef
57. Ogar J, Slama H, Dronkers N et al (2005) Apraxia of speech: an overview. Neurocase 11:427鈥?32 CrossRef
58. Ogar J, Willock S, Baldo J et al (2006) Clinical and anatomical correlates of apraxia of speech. Brain Lang 97:343鈥?50 CrossRef
59. Otto M, Ludolph AC, Landwehrmeyer B et al (2011) German consortium for frontotemporal lobar degeneration. Nervenarzt 82:1002鈥?005 CrossRef
60. Pasquier F, Grymonprez L, Lebert F, van der Linden M (2001) Memory impairment differs in frontotemporal dementia and Alzheimer鈥檚 disease. Neurocase 7:161鈥?71 CrossRef
61. Poeck K, Luzzatti C (1988) Slowly progressive aphasia in three patients. The problem of accompanying neuropsychological deficit. Brain 111:151鈥?68 CrossRef
62. Procter AW, Qurne M, Francis PT (1999) Neurochemical features of frontotemporal dementia. Dement Geriatr Cogn Disord 10(Suppl 1):80鈥?4 CrossRef
63. Rabinovici GD, Jagust WJ, Furst AJ et al (2008) A beta amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann Neurol 64:388鈥?01 CrossRef
64. Rascovsky K, Hodges JR, Knopman D et al (2011) Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 134:2456鈥?477 CrossRef
65. Rosen HJ, Gorno-Tempini ML, Goldman WP et al (2002) Patterns of brain atrophy in frontotemporal dementia and semantic dementia. Neurology 58:198鈥?08 CrossRef
66. Rosso SM, Donker Kaat L, Baks T et al (2003) Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 126:2016鈥?022 CrossRef
67. Schlachetzki JC, Schmidtke K, Beckervordersandforth J et al (2009) Frequency of progranulin mutations in a German cohort of 79 frontotemporal dementia patients. J Neurol 256:2043鈥?051 CrossRef
68. Schneider JA, Aggarwal NT, Barnes L et al (2009) The neuropathology of older persons with and without dementia from community versus clinic cohorts. J Alzheimers Dis 18:691鈥?01
69. Seeley WW, Carlin DA, Allman JM et al (2006) Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol 60:660鈥?67 CrossRef
70. Snowden JS (1999) Semantic dysfunction in frontotemporal lobar degeneration. Dement Geriatr Cogn Disord 10(Suppl 1):33鈥?6 CrossRef
71. Snowden JS, Bathgate D, Varma A et al (2001) Distinct behavioural profiles in frontotemporal dementia and semantic dementia. J Neurol Neurosurg Psychiatry 70:323鈥?32 CrossRef
72. Snowden JS, Neary D, Mann D (1996) Fronto-temporal lobar degeneration: fronto-temporal dementia, progressive aphasia, semantic dementia. Churchill Livingstone, New York
73. Sparks DL, Markesbery WR (1991) Altered serotonergic and cholinergic synaptic markers in Pick鈥檚 disease. Arch Neurol 48:796鈥?99 CrossRef
74. Strong MJ (2008) The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis. Amyotroph Lateral Scler 9:323鈥?38 CrossRef
75. Strong MJ, Yang W (2011) The frontotemporal syndromes of ALS. Clinicopathological correlates. J Mol Neurosci 45(3):648鈥?55 CrossRef
76. Thompson SA, Patterson K, Hodges JR (2003) Left/right asymmetry of atrophy in semantic dementia: behavioral-cognitive implications. Neurology 61:1196鈥?203 CrossRef
77. Tsermentseli S, Leigh PN, Goldstein LH (2011) The anatomy of cognitive impairment in amyotrophic lateral sclerosis: more than frontal lobe dysfunction. Cortex [Epub ahead of print]
78. Wicklund MR, Mokri B, Drubach DA et al (2011) Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD. Neurology 76:1377鈥?382 CrossRef
79. Yang Y, Schmitt HP (2001) Frontotemporal dementia: evidence for impairment of ascending serotoninergic but not noradrenergic innervation. Immunocytochemical and quantitative study using a graph method. Acta Neuropathol 101:256鈥?70 - 作者单位：Prof. Dr. K. Witt (1)
G. Deuschl (1)
T. Bartsch (1)
1. Klinik f眉r Neurologie, Universit盲tsklinikum Schleswig-Holstein, Campus Kiel, Schittenhelmstr. 10, 24105, Kiel, Deutschland
文摘