T/NK cell lymphoma presenting as a ¡°blocked nose?

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• 作者：Naomi Ketharanathan ; Peter Jan van Kipshagen ; Wies Vasmel ; Ellis Barb¨¦ and Nico de Vries
• 关键词：Nasal T/NK cell lymphoma ; Sinonasal lymphoma ; Nasal obstruction
• 刊名：European Archives of Oto-Rhino-Laryngology
• 出版年：2008
• 出版时间：September, 2008
• 年：2008
• 卷：265
• 期：9
• 页码：1131-1134
• 全文大小：345.6 KB

文摘

We present the case of a 63-year-old Caucasian male who complained of persistent rhinitis and sinusitis accompanied by a total left-sided nasal blockage. The diagnosis nasal T/NK cell lymphoma was established by histopathological investigation. This case was diagnosed as stage IE lymphoma as no other sites were involved. The patient was treated with CHOP (cyclophosfamide, doxorubicin, vincristin and prednisone) chemotherapy and involved-field radiotherapy. The nasal T/NK cell lymphoma is a rare malignancy, which is known to have an extremely aggressive and destructive course. The mainstay of treatment is locoregional radiotherapy combined with chemotherapy, depending on disease stage. A high index of clinical suspicion is imperative to ensure early diagnosis and ultimately improve disease outcome.