The influence of vasovagal response on the coagulation system

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• 作者：Markus Kraemer ; Markus Kuepper ; Andrea Nebe-vom Stein ; Ulrich Sorgenfrei and Rolf R. Diehl
• 关键词：Vasovagal response ; Coagulation ; von ; Willebrand ; factor
• 刊名：Clinical Autonomic Research
• 出版年：2010
• 出版时间：April, 2010
• 年：2010
• 卷：20
• 期：2
• 页码：105-111
• 全文大小：225.9 KB

文摘

Background Vasovagal response (VVR) is provoked by a reduced venous blood return to the heart as a reaction to orthostatic stress and to haemorrhage. Recently, two cases were reported showing elevated plasma concentration of von-Willebrand-factor (VWF) and factor VIII (FVIII) after VVR due to venapuncture. Although the effect of epinephrine as trigger for VWF liberation is known, a connection between VVR and activation of the coagulation system has not been studied systematically.