Elevated urinary urea by high-protein diet could be one of the inducements of bladder disorders
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- 作者：Ming Liu ; Min Li ; Jiangfeng Liu ; Hongkai Wang…
- 关键词：Urea ; Protein ; protein interaction network ; Cytoscape ; Inflammation ; Cell cycle ; Pathways in cancer ; Bladder cancer
- 刊名：Journal of Translational Medicine
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：14
- 期：1
- 全文大小：7,647 KB
- 刊物主题：Biomedicine general; Medicine/Public Health, general;
- 出版者：BioMed Central
- ISSN：1479-5876
文摘
Background Previous work found that urea accumulation in urothelial cells caused by urea transporter B knockout led to DNA damage and apoptosis that contributed to the carcinogenesis. The purpose of this study is to explore the potential connection between high urinary urea concentration and the bladder disorders.