MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1
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- 作者：Guang-jun Zhang ; Jian-shui Li ; He Zhou…
- 关键词：Colorectal cancer ; miR ; 106b ; DLC1 ; Migration ; Invasion ; Prognosis
- 刊名：Journal of Experimental & Clinical Cancer Research
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：34
- 期：1
- 全文大小：1,796 KB
- 刊物主题：Oncology; Cancer Research;
- 出版者：BioMed Central
- ISSN：1756-9966
文摘
Background Growing evidence suggests that microRNAs (miRNAs) play an important role in tumor development, progression and metastasis. Aberrant miR-106b expression has been reported in several cancers. However, the role and underlying mechanism of miR-106 in colorectal cancer (CRC) have not been addressed.