Repeated Exposure to “meaningless-Pseudowords Modulates LPC, but Not N(FN)400

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• 作者：Beatriz Bermúdez-Margaretto ; David Beltrán ; Alberto Domínguez…
• 关键词：Reading ; ERP methodology ; FN400 ; LPC ; TANCOVA
• 刊名：Brain Topography
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：28
• 期：6
• 页码：838-851
• 全文大小：2,110 KB
• 参考文献：Allison T, McCarthy G, Nobre A, Puce A, Belger A (1994) Human extrastriate visual cortex and the perception of faces, words, numbers, and colors. Cereb Cortex 4(5):544-54. doi:10.-093/?cercor/-.-.-44 CrossRef PubMed
  Batterink L, Neville H (2011) Implicit and explicit mechanisms of word learning in a narrative context: an event-related potential study. J Cogn Neurosci 23(11):3181-196. doi:10.-162/?jocn_?a_-0013 PubMed Central CrossRef PubMed
  Bentin S, Mouchetant-Rostaing Y, Giard M, Echallier J, Pernier J (1999) ERP manifestations of processing printed words at different psycholinguistic levels: time course and scalp distribution. J Cogn Neurosci 11(3):235-60. doi:10.-162/-89892999563373 CrossRef PubMed
  Borovsky A, Kutas M, Elman J (2010) Learning to use words: event-related potentials index single-shot contextual word learning. Cognition 116(2):289-96. doi:10.-016/?j.?cognition.-010.-5.-04 PubMed Central CrossRef PubMed
  Breitenstein C, Zwitserlood P, de Vries MH, Feldhues C, Knecht S, Dobel C (2007) Five days versus a lifetime: intense associative vocabulary training generates lexically integrated words. Restor Neurol Neurosci 25(5):493-00PubMed
  Bridger EK, Bader R, Kriukova O, Unger K, Mecklinger A (2012) The FN400 is functionally distinct from the N400. Neuroimage 63(3):1334-342. doi:10.-016/?j.?neuroimage.-012.-7.-47 CrossRef PubMed
  Brunet D, Murray MM, Michel CM (2011) Spatiotemporal analysis of multichannel EEG: CARTOOL. Comput Intell Neurosci 2011:2. doi:10.-155/-011/-13870
  Carreiras M, Vergara M, Barber H (2005) Early event-related potential effects of syllabic processing during visual word recognition. J Cogn Neurosci 17(11):1803-817. doi:10.-162/-898929057745892-7 CrossRef PubMed
  Clark HH (1973) The language-as-fixed-effect fallacy: a critique of language statistics in psychological research. J Verbal Learn Verbal Behav 12(4):335-59. doi:10.-016/?S0022-5371(73)80014-3 CrossRef
  Clay F, Bowers JS, Davis CJ, Hanley DA (2007) Teaching adults new words: the role of practice and consolidation. J Exp Psychol Learn Mem Cogn 33(5):970. doi:10.-037/-278-7393.-3.-.-70 CrossRef PubMed
  Cohen L, Dehaene S (2004) Specialization within the ventral stream: the case for the visual word form area. Neuroimage 22(1):466-76. doi:10.-016/?j.?neuroimage.-003.-2.-49 CrossRef PubMed
  Davis CJ, Perea M (2005) BuscaPalabras: a program for deriving orthographic and phonological neighborhood statistics and other psycholinguistic indices in Spanish. Behav Res Methods 37(4):665-71. doi:10.-758/?BF03192738 CrossRef PubMed
  de Peralta Menendez RG, Andino SG, Lantz G, Michel CM, Landis T (2001) Noninvasive localization of electromagnetic epileptic activity. I. Method descriptions and simulations. Brain Topogr 14(2):131-37. doi:10.-023/?A:-012944913650 CrossRef
  de Peralta Menendez RG, Andino SG (1999) Distributed source models: standard solutions and new developments. Analysis of neurophysiological brain functioning. Springer, Berlin, pp 176-01. doi:10.-007/-78-3-642-60007-4_-0 CrossRef
  Dobel C, Jungh?fer M, Breitenstein C, Klauke B, Knecht S, Pantev C, Zwitserlood P (2010) New names for known things: on the association of novel word forms with existing semantic information. J Cogn Neurosci 22(6):1251-261. doi:10.-162/?jocn.-009.-1297 CrossRef PubMed
  Dumay N, Gaskell MG (2007) Sleep-associated changes in the mental representation of spoken words. Psychol Sci 18(1):35-9. doi:10.-111/?j.-467-9280.-007.-1845.?x CrossRef PubMed
  Fink GR, Halligan PW, Marshall JC, Frith CD, Frackowiak R, Dolan RJ (1997) Neural mechanisms involved in the processing of global and local aspects of hierarchically organized visual stimuli. Brain 120(10):1779-791. doi:10.-093/?brain/-20.-0.-779 CrossRef PubMed
  Fonseca LC, Tedrus GM, Gilbert MAP (2006) Event related potentials during the visual discrimination of words and pseudowords by children. Arq Neuropsiquiatr 64(3A):553-58. doi:10.-590/?S0004-282X200600040000- CrossRef PubMed
  Frishkoff GA, Perfetti CA, Collins-Thompson K (2010) Lexical quality in the brain: ERP evidence for robust word learning from context. Dev Neuropsychol 35(4):376-03. doi:10.-080/-7565641.-010.-80915 PubMed Central CrossRef PubMed
  Gallés NS (2000) LEXESP: Léxico informatizado del espa?ol: Edicions Universitat Barcelona
  Genovese CR, Lazar NA, Nichols T (2002) Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 15(4):870-78. doi:10.-006/?nimg.-001.-037 CrossRef PubMed
  Groening K, Brodbeck V, Moeller F, Wolff S, van Baalen A, Michel CM, Siniatchkin M (2009) Combination of EEG–fMRI and EEG source analysis improves interpretation of spike-associated activation networks in paediatric pharmacoresistant focal epilepsies. Neuroimage 46(3):827-33. doi:10.-016/?j.?neuroimage.-009.-2.-26 CrossRef PubMed
  Groh-Bordin C, Zimmer HD, Ecker
• 作者单位：Beatriz Bermúdez-Margaretto (1)
  David Beltrán (2)
  Alberto Domínguez (3)
  Fernando Cuetos (1)
  
  1. Facultad de Psicología, Universidad de Oviedo, Plaza Feijoo, s/n, 33010, Oviedo, Spain
  2. Laboratorio Neurocog, Universidad de La Laguna, Tenerife, Spain
  3. Facultad de Psicología, Universidad de La Laguna, Tenerife, Spain
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Neurosciences
  Psychiatry
  Neurology
  
• 出版者：Springer New York
• ISSN：1573-6792

文摘

Training readers to recognize pseudowords could decrease the processing differences between them and real words while clarifying the lexical acquisition processes. We analyze the effect of pseudoword repetition through the recording of EEG during a lexical decision task. Results showed a functional dissociation between two well-known ERP components: FN400 (Frontal N400, traditionally related to semantic processes) and LPC (Late Positive Complex, related to memory processes). On the one hand, FN400 was unaffected by pseudoword repetition and showed the typical lexicality effect. On the other hand, topographic and neural source analyses showed that LPC amplitude increased across repetitions, causing the lexicality effect to disappear, with the left inferior frontal, left superior temporal and right superior frontal gyri identified as the most likely neural sources. The lack of repetition effect on FN400 suggests that this component is unrelated to familiarity processes and is only influenced by semantic differences between stimuli. The LPC observations, however, reflect the construction and strengthening of visual memory traces for repeated pseudowords, facilitating their processing over the course of the task. Keywords Reading ERP methodology FN400 LPC TANCOVA