Evolution of substrate recognition sites (SRSs) in cytochromes P450 from Apiaceae exemplified by the CYP71AJ subfamily
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- 作者：Bjørn Dueholm ; Célia Krieger ; Damian Drew ; Alexandre Olry…
- 关键词：Cytochrome P450 ; Furanocoumarin ; Hydroxycoumarin ; Apiaceae ; Apioideae ; Gene duplication ; Plant ; insect coevolution ; CYP71AJ subfamily ; Substrate recognition sites (SRSs) ; Pastinaca sativa
- 刊名：BMC Evolutionary Biology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：15
- 期：1
- 全文大小：1,821 KB
- 刊物主题：Evolutionary Biology; Animal Systematics/Taxonomy/Biogeography; Entomology; Genetics and Population Dynamics; Life Sciences, general;
- 出版者：BioMed Central
- ISSN：1471-2148
文摘
Background Large proliferations of cytochrome P450 encoding genes resulting from gene duplications can be termed as ‘blooms’, providing genetic material for the genesis and evolution of biosynthetic pathways. Furanocoumarins are allelochemicals produced by many of the species in Apiaceaous plants belonging to the Apioideae subfamily of Apiaceae and have been described as being involved in the defence reaction against phytophageous insects.