Prevalence and Associated Factors of Erectile Dysfunction in Patients With Moderate to Severe Psoriasis and Healthy Population: A Comparative Study Considering Physical and Psychological Factors

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• 作者：Alejandro Molina-Leyva ; Ignacio Molina-Leyva…
• 关键词：Anxiety ; Organic/medical factors ; Psychological factors ; Depression ; Erectile dysfunction ; Psoriasis
• 刊名：Archives of Sexual Behavior
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：45
• 期：8
• 页码：2047-2055
• 全文大小：428 KB
• 刊物类别：Behavioral Science
• 刊物主题：Psychology
  Sexual Behavior
  Social Sciences
  
• 出版者：Springer Netherlands
• ISSN：1573-2800
• 卷排序：45

文摘

Recent studies have shown that psoriasis is associated with an increased prevalence of erectile dysfunction. To our knowledge, no comparative study has considered simultaneously the role of organic factors and psychological factors in this process. We performed a prospective case series study matched by age to explore the prevalence of erectile dysfunction in psoriasis patients compared to a healthy population and to investigate the role of anxiety, depression, and cardiovascular risk factors in the relationship between psoriasis and erectile dysfunction. The healthy group was matched by frequency to cases by age. Seventy-nine patients with moderate to severe psoriasis and 79 healthy controls participated in the study. Participants completed the Massachusetts General Hospital Sexual Functioning Questionnaire and the Hospital Anxiety and Depression Scale. Psoriasis patients had an increased prevalence of erectile dysfunction in comparison to controls, 34.2 vs. 17.7 % (p < .05). Multivariate analysis showed a significant association between erectile dysfunction and age, smoking and anxiety/depression, but not with psoriasis per se. In conclusion, the higher prevalence of smoking and anxiety/depression among patients with moderate to severe psoriasis probably explains the higher prevalence of erectile dysfunction in this population.