Intentional avoidance of the esophagus using intensity modulated radiation therapy to reduce dysphagia after palliative thoracic radiation
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- 作者：Patrick V. Granton ; David A. Palma ; Alexander V. Louie
- 关键词：Dysphagia ; Esophagitis ; Normal tissue complication probability ; Lyman ; Kutcher ; Burman model ; Palliative care
- 刊名：Radiation Oncology
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：12
- 期：1
- 全文大小：1251KB
- 刊物主题：Cancer Research; Oncology; Radiotherapy; Imaging / Radiology;
- 出版者：BioMed Central
- ISSN：1748-717X
- 卷排序：12
文摘
BackgroundPalliative thoracic radiotherapy is an effective technique to alleviate symptoms of disease burden in advanced-stage lung cancer patients. Previous randomized controlled studies demonstrated a survival benefit in patients with good performance status at radiation doses of 35Gy10 or greater but with an increased incidence of esophagitis. The objective of this planning study was to assess the potential impact of esophageal-sparing IMRT (ES-IMRT) compared to the current standard of care using parallel-opposed pair beams (POP).