Long-Term Effects of the Collagenase of the Bacterium Clostridium histolyticum for the Treatment of Capsular Fibrosis After Silicone Implants
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- 作者：Sebastian Fischer ; Yannick Diehm ; Thomas Henzler…
- 关键词：Silicone implants ; Collagenase ; Capsular contracture ; Capsular fibrosis
- 刊名：Aesthetic Plastic Surgery
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：41
- 期：1
- 页码：211-220
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Plastic Surgery; Otorhinolaryngology;
- 出版者：Springer US
- ISSN：1432-5241
- 卷排序：41
文摘
BackgroundCapsular contracture remains the most frequent long-term complication after augmentation mammoplasty with silicone implants. Thereby, the main part of the fibrotic capsule is collagen. The collagenase of the bacterium Clostridium histolyticum is approved for the treatment of fibrotic diseases and has been demonstrated to be effective for capsular fibrosis treatment in the short term. However, long-term effectiveness is currently unknown but mandatory for clinical utilization.