RBL-2H3 cells are an imprecise model for mast cell mediator release

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• 作者：Egle Passante ; Carsten Ehrhardt ; Helen Sheridan and Neil Frankish
• 关键词：RBL ; 2H3 ; Mast cell ; Toll ; like receptors
• 刊名：Inflammation Research
• 出版年：2009
• 出版时间：September, 2009
• 年：2009
• 卷：58
• 期：9
• 页码：611-618
• 全文大小：313.9 KB

文摘

Objective The cell line, RBL-2H3, has been widely used as a mast cell model though much of the data is contradictory. The aim of this study is to assess the RBL-2H3 cell line as an in vitro model for degranulation studies.