Investigation of the Tsix gene regulatory region in vole Microtus rossiaemeridionalis

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• 作者：O. A. Zhukova ; E. A. Elisaphenko and S. M. Zakian
• 刊名：Russian Journal of Genetics
• 出版年：2010
• 出版时间：October 2010
• 年：2010
• 卷：46
• 期：10
• 页码：1229-1232
• 全文大小：309.6 KB

文摘

The Tsix regulatory region was examined in vole Microtus rossiaemeridionalis. The minimal promoter region, three potential enhancer regulatory elements and one transcription suppressor element were identified. The enhancer regions contained potential binding sites of transcription activators, while in the region of putative silencer contained potential binding site of the ARP1 (NR2F2) protein. This protein can play the role of either activator or repressor depending on the promoter context.