Characterization of tubular liquid crystal structure in embryonic stem cell derived embryoid bodies
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- 作者：MengMeng Xu ; Odell D. Jones ; Liyang Wang ; Xin Zhou ; Harry G. Davis…
- 关键词：Liquid crystal ; Phase transition ; Embryoid body ; Embryonic stem cell
- 刊名：Cell & Bioscience
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：7
- 期：1
- 全文大小：6109KB
- 刊物主题：Cell Biology; Microbiology; Stem Cells; Neurobiology; Proteomics;
- 出版者：BioMed Central
- ISSN：2045-3701
- 卷排序：7
文摘
BackgroundMassive liquid crystal droplets have been found during embryonic development in more than twenty different tissues and organs, including the liver, brain and kidney. Liquid crystal deposits have also been identified in multiple human pathologies, including vascular disease, liver dysfunction, age-related macular degeneration, and other chronic illnesses. Despite the involvement of liquid crystals in such a large number of human processes, this phenomenon is poorly understood and there are no in vitro systems to further examine the function of liquid crystals in biology.