Chiral NMR Solvating Additives for Differentiation of Enantiomers
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- 作者：Gloria Uccello-Barretta (12)
Federica Balzano (12) - 关键词：Chiral discrimination ; Chiral solvating agents ; Enantiomeric excess ; Nuclear magnetic resonance
- 刊名：Topics in Current Chemistry
- 出版年：2013
- 出版时间：2013
- 年：2013
- 卷：341
- 期：1
- 页码：69-131
- 全文大小：1,825 KB
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Federica Balzano (12)
12. Dipartimento di Chimica e Chimica Industriale, Universit脿 di Pisa, via Risorgimento 35, 56126, Pisa, Italy - ISSN：1436-5049
文摘
This chapter will describe the general features and main categories of chiral solvating agents (CSAs) for NMR spectroscopy, spanning from low-medium sized CSAs to macrocyclic ones. CSAs based on chiral ionic liquids (CILs) will be introduced in view of their increasing popularity, and, finally, a short paragraph will be dedicated to special applications of CSAs in particular experimental conditions. Several valuable works, which are mainly devoted to investigate enantiodifferentiation mechanisms by NMR, will not be discussed. The main objective is to identify the current trend in the research areas dedicated to the development of new CSAs for NMR spectroscopy.