Hexokinase 2 drives glycogen accumulation in equine endometrium at day 12 of diestrus and pregnancy
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BackgroundSecretion of histotroph during the prolonged pre-implantation phase in mares is crucial to pregnancy maintenance, manifested as increased embryonic loss in mares with age-related endometrial degeneration. Glycogen content of uterine histotroph is higher during the progesterone-dominated phase of the estrous cycle in mares, but regulatory mechanisms are not well understood.

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