A next-generation microarray further reveals stage-enriched gene expression pattern in the blood fluke Schistosoma japonicum
详细信息 查看全文
- 作者：Pengfei Cai ; Shuai Liu ; Xianyu Piao ; Nan Hou ; Hong You…
- 关键词：Schistosoma japonicum ; Microarray ; Gene profiling ; Stage ; enriched expression ; Developmental biology
- 刊名：Parasites & Vectors
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：2105KB
- 刊物主题：Parasitology; Entomology; Tropical Medicine; Infectious Diseases; Veterinary Medicine/Veterinary Science; Virology;
- 出版者：BioMed Central
- ISSN：1756-3305
- 卷排序：10
文摘
BackgroundSchistosomiasis is caused by infection with blood flukes of the genus Schistosoma, and ranks, in terms of disability-adjusted life years (DALYs), as the third most important neglected tropical disease. Schistosomes have several discrete life stages involving dramatic morphological changes during their development, which require subtle gene expression modulations to complete the complex life-cycle.