Enrofloxacin degradation in broiler chicken manure under various laboratory conditions
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- 作者：Marko Slana ; Marija Sollner-Dolenc
- 关键词：Enrofloxacin degradation kinetics ; Degradation product ; Desethylene ; enrofloxacin ; Aerobic and aerobic incubation ; Non ; sterile and sterile conditions ; Light/dark regime
- 刊名：Environmental Science and Pollution Research
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：23
- 期：5
- 页码：4422-4429
- 全文大小：457 KB
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Marija Sollner-Dolenc (2)
1. Krka, d. d., Novo mesto, Šmarješka cesta 6, 8501, Novo mesto, Slovenia
2. Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia - 刊物类别：Earth and Environmental Science
- 刊物主题：Environment
Environment
Atmospheric Protection, Air Quality Control and Air Pollution
Waste Water Technology, Water Pollution Control, Water Management and Aquatic Pollution
Industrial Pollution Prevention - 出版者：Springer Berlin / Heidelberg
- ISSN：1614-7499
文摘
The rate of degradation of enrofloxacin in broiler chicken manure has been characterized in the laboratory according to the CVMP guideline on determining the fate of veterinary medicinal products in manure. Degradation was followed in a flow-through system under aerobic and anaerobic conditions, in the dark and in the presence of light. The rate of degradation of enrofloxacin and the formation of its degradation products are dependent on laboratory conditions. A rapid degradation of enrofloxacin in the dark was noticed, where a shorter degradation half-life under aerobic (DT50 = 59.1 days), comparing to anaerobic conditions (DT50 = 88.9 days), was determined. The presence of light slowed down the enrofloxacin degradation half-life, which was significantly shorter under aerobic (DT50 = 115.0 days), comparing to anaerobic conditions (DT50 = 190.8 days). Desethylene-enrofoxacin was the only degradation product formed, its concentrations ranged from 2.5 to 14.9 %. The concentration of the degradation product was approximately 2.5-fold higher under aerobic conditions. Enrofloxacin degradation in sterile manure incubated under sterile conditions was marginal comparing to non-sterile conditions; after 120 days of incubation, approximately 80 % of enrofloxacin was still present in manure and only 1 % of desethylene-enrofloxacin was formed. The present work demonstrates that enrofloxacin degradation in chicken manure is relatively fast when incubated in the dark under aerobic conditions which is the recommended incubation system for chicken manure according to CVMP guideline.