Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits

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• 作者：Felipe Jim茅nez-Aspee ; Maria Rosa Alberto…
• 关键词：Eulychnia acida ; Cactaceae ; Copao ; Anti ; inflammatory capacity
• 刊名：Plant Foods for Human Nutrition
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：70
• 期：2
• 页码：135-140
• 全文大小：640 KB
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• 作者单位：Felipe Jim茅nez-Aspee (1)
  Maria Rosa Alberto (2)
  Cristina Quispe (1)
  Maria del Pilar Caramantin Soriano (1)
  Cristina Theoduloz (3)
  Iris Catiana Zampini (2)
  Maria Ines Isla (2)
  Guillermo Schmeda-Hirschmann (1)
  
  1. Laboratorio de Qu铆mica de Productos Naturales, Universidad de Talca, Instituto de Qu铆mica de Recursos Naturales, Casilla 747, Talca, Chile
  2. Laboratorio de Investigaci贸n de Productos Naturales (LIPRON), Instituto de Qu铆mica del NOA (INQUINOA, CONICET), Universidad Nacional de Tucum谩n, San Miguel de Tucum谩n, Argentina
  3. Laboratorio de Cultivo Celular, Facultad de Ciencias de la Salud, Universidad de Talca, Casilla 747, 3460000, Talca, Chile
  
• 刊物主题：Food Science; Chemistry/Food Science, general; Nutrition; Ecology; Plant Physiology;
• 出版者：Springer US
• ISSN：1573-9104

文摘

Copao (Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100聽渭g/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit.