The role of mobility and health disparities on the transmission dynamics of Tuberculosis
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- 作者：Victor Moreno ; Baltazar Espinoza ; Kamal Barley…
- 关键词：Tuberculosis ; Residence times ; Heterogeneity ; Exogenous re ; infection ; Direct first time infection rate ; Metapopulation model
- 刊名：Theoretical Biology and Medical Modelling
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：14
- 期：1
- 全文大小：2128KB
- 刊物主题：Biomedicine general; Systems Biology; Physiological, Cellular and Medical Topics; Statistics for Life Sciences, Medicine, Health Sciences; Bioinformatics; Infectious Diseases;
- 出版者：BioMed Central
- ISSN：1742-4682
- 卷排序：14
文摘
BackgroundThe transmission dynamics of Tuberculosis (TB) involve complex epidemiological and socio-economical interactions between individuals living in highly distinct regional conditions. The level of exogenous reinfection and first time infection rates within high-incidence settings may influence the impact of control programs on TB prevalence. The impact that effective population size and the distribution of individuals’ residence times in different patches have on TB transmission and control are studied using selected scenarios where risk is defined by the estimated or perceive first time infection and/or exogenous re-infection rates.