The study of adaptation mechanisms of <i>Yarrowia lipolyticai> yeast to alkaline conditions by means of proteomics

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• 作者：M. A. Guseva ; E. Yu. Epova ; L. I. Kovalev and A. B. Shevelev
• 刊名：Applied Biochemistry and Microbiology
• 出版年：2010
• 出版时间：May, 2010
• 年：2010
• 卷：46
• 期：3
• 页码：307-312
• 全文大小：229.1 KB

文摘

Using proteomic technologies—two-dimensional electrophoresis in denaturing conditions in combination with mass spectroscopy of MALDI-TOF proteins—we demonstrated, for the first time, that the most noticeable alteration of protein composition of a Yarrowia lipolytica cell during adaptation to alkaline conditions was an increase of mitochondrial proteins relatively to proteins of cytoplasm.