Improved anticancer delivery of paclitaxel by albumin surface modification of PLGA nanoparticles
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- 作者：Mehdi Esfandyari-Manesh ; Seyed Hossein Mostafavi…
- 关键词：PLGA ; Surface modified nanoparticles ; Drug delivery ; Albumin ; Paclitaxel
- 刊名：DARU Journal of Pharmaceutical Sciences
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：23
- 期：1
- 全文大小：1,674 KB
- 刊物主题：Pharmaceutical Sciences/Technology; Pharmacology/Toxicology; Medicinal Chemistry;
- 出版者：BioMed Central
- ISSN：2008-2231
文摘
Background Nanoparticles (NPs) play an important role in anticancer delivery systems. Surface modified NPs with hydrophilic polymers such as human serum albumin (HSA) have long half-life in the blood circulation system.