Dentin dysplasia type I—novel findings in deciduous and permanent teeth

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• 作者：Xin Ye ; Kunyang Li ; Ling Liu ; Fangfang Yu ; Fu Xiong ; Yun Fan…
• 刊名：BMC Oral Health
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：15
• 期：1
• 全文大小：3,675 KB
• 刊物主题：Dentistry; Oral and Maxillofacial Surgery;
• 出版者：BioMed Central
• ISSN：1472-6831

文摘

Background Dentin dysplasia type I (DD-I) is a rare autosomal dominant hereditary disorder which seriously affects the root development of teeth, causing spontaneous tooth loss (in teenagers). At present, the study of DD-I focuses on familial and phenotypic analyses and reports regarding the ultrastructural study of DD-I are few. The purpose of this study was to clarify and discuss the clinical, histopathological, and ultrastructural features of the dentin defects in DD-I. In addition, the study further explores the root development and provides clues for uncovering virulent genes associated with the disease.