Lgr5 expression is a valuable prognostic factor for colorectal cancer: evidence from a meta-analysis

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• 作者：Yangyan Jiang ; Wenlu Li ; Xin He ; Hongbo Zhang ; Fangzhen Jiang ; Zhigang Chen
• 关键词：Lgr5 ; Prognostic value ; Clinical ; pathological differences ; Colorectal cancer ; Meta ; analysis
• 刊名：BMC Cancer
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：670 KB
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• 作者单位：Yangyan Jiang (1)
  Wenlu Li (2)
  Xin He (3)
  Hongbo Zhang (4)
  Fangzhen Jiang (5)
  Zhigang Chen (6)
  
  1. Department of UItrasonic diagnosis, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
  2. Department of Pharmacology, Zhejiang University School of pharmacy, Hangzhou, China
  3. Department of Hematology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
  4. Department of Neurology, Third people’s hospital, Huzhou, China
  5. Department of Plastic surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
  6. Department of Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
  
• 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2407

文摘

Background Lgr5 has recently been identified as a reliable biomarker of cancer stem cells (CSCs) in colorectal cancer (CRC); however, its prognostic value is still controversial.