Closed-loop for type 1 diabetes – an introduction and appraisal for the generalist

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• 作者：Lia Bally ; Hood Thabit ; Roman Hovorka
• 关键词：Type 1 diabetes ; Artificial pancreas ; Closed ; loop ; Glucose control
• 刊名：BMC Medicine
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：15
• 期：1
• 全文大小：520KB
• 刊物主题：Medicine/Public Health, general; Biomedicine, general;
• 出版者：BioMed Central
• ISSN：1741-7015
• 卷排序：15

文摘

BackgroundRapid progress over the past decade has been made with the development of the ‘Artificial Pancreas’, also known as the closed-loop system, which emulates the feedback glucose-responsive functionality of the pancreatic beta cell. The recent FDA approval of the first hybrid closed-loop system makes the Artificial Pancreas a realistic therapeutic option for people with type 1 diabetes. In anticipation of its advent into clinical care, we provide a primer and appraisal of this novel therapeutic approach in type 1 diabetes for healthcare professionals and non-specialists in the field.