Follicular thyroid carcinoma but not adenoma recruits tumor-associated macrophages by releasing CCL15
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- 作者：Feng-Jiao Huang ; Xiao-Yi Zhou ; Lei Ye ; Xiao-Chun Fei ; Shu Wang ; Weiqing Wang…
- 关键词：Follicular thyroid carcinoma ; Follicular adenoma ; Tumor ; associated macrophages ; CCL15
- 刊名：BMC Cancer
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：16
- 期：1
- 全文大小：2,916 KB
- 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1471-2407
文摘
Background The differential diagnosis of follicular thyroid carcinoma (FTC) and follicular adenoma (FA) before surgery is a clinical challenge. Many efforts have been made but most focusing on tumor cells, while the roles of tumor associated macrophages (TAMs) remained unclear in FTC. Here we analyzed the differences between TAMs in FTC and those in FA.