Stromal factors involved in human prostate cancer development, progression and castration resistance
详细信息 查看全文
- 作者：Noemi Eiro ; Jesus Fernandez-Gomez…
- 关键词：Cancer ; associated fibroblasts (CAFs) ; Tumor stroma ; Metastatic cancer ; Castration ; resistant prostate cancer ; Androgen deprivation therapy
- 刊名：Journal of Cancer Research and Clinical Oncology
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：143
- 期：2
- 页码：351-359
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Oncology; Cancer Research; Internal Medicine; Hematology;
- 出版者：Springer Berlin Heidelberg
- ISSN：1432-1335
- 卷排序：143
文摘
PurposeTo detect new predictive markers from the prostate cancer tissue, to study the expression by cultured cancer-associated fibroblasts (CAFs) of stromal factors implicated in prostate carcinogenesis, and to compare their expressions in localized, metastatic, castration-sensitive (CSCP), castration-resistant prostate tumors (CRCP) as well as in fibroblasts from benign prostatic hyperplasia (BPH).