Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report

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• 作者：Jean Carlos Barbosa Ferreira ; Angélica Ferreira Oton-Leite…
• 关键词：Granular cell tumor ; Diagnosis ; Immunohistochemistry ; Squamous cell carcinoma ; Case report
• 刊名：BMC Research Notes
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：1803KB
• 刊物主题：Biomedicine, general; Medicine/Public Health, general; Life Sciences, general;
• 出版者：BioMed Central
• ISSN：1756-0500
• 卷排序：10

文摘

BackgroundGranular cell tumor is a rare benign tumor that can present a pseudoepitheliomatous hyperplasia of the covering epithelium. This lesion is not encapsulated and can be characterized by a pseudo invasive growth pattern, represented by the tumoral cells that infiltrate between adjacent connective tissue elements. Diagnostic difficulties may arise because histopathological features of the pronounced pseudoepitheliomatous hyperplasia can be confused with a well-differentiated oral squamous cell carcinoma. The aim of this case report is to demonstrate the role of an immunohistochemical panel in the diagnosis of a granular cell tumor in the tongue with clinical and microscopic features resembling an oral squamous cell carcinoma.