Amniopatch: Way Forward for Mid-trimester Premature Rupture of Membranes (PROM)

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• 作者：Ashutosh Gupta ; Anjila Aneja ; Rupam Arora ; Renu Sheghal…
• 关键词：Hardening ; Elastic ; Rupture ; Amniopatch ; Fetoscopy
• 刊名：Journal of Fetal Medicine
• 出版年：2014
• 出版时间：March 2014
• 年：2014
• 卷：1
• 期：1
• 页码：45-48
• 全文大小：526KB
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  6.Reddy UM, Shah SS, Nemiroff RL, Ballas SK, Hyslop T, Chen J, et al. In vitro sealing of punctured fetal membranes: potential treatment for midtrimester premature rupture of membranes. Am J Obstet Gynecol. 2001;185:1090鈥?.PubMed CrossRef
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• 作者单位：Ashutosh Gupta (1)
  Anjila Aneja (2)
  Rupam Arora (3)
  Renu Sheghal (4)
  Pooja Gupta (3)
  
  1. Department of Fetal Medicine & Medical Genetics, Max Super Speciality West, 1, Press Enclave Road, Saket, New Delhi, 110017, India
  2. Department of Obstetrics & Gynecology; Minimal Access, Fortis Memorial Research Institute, Gurgaon, Haryana, India
  3. Department of Obstetrics & Gynecology, Max Balaji Hospital, New Delhi, India
  4. Department of Obstetrics & Gynecology, Artemis Health Institute, Gurgaon, Haryana, India
  
• 刊物类别：Maternal and Child Health; Diagnostic Radiology; Ultrasound; Obstetrics/Perinatology; Reproductive M
• 刊物主题：Maternal and Child Health; Diagnostic Radiology; Ultrasound; Obstetrics/Perinatology; Reproductive Medicine;
• 出版者：Springer India
• ISSN：2348-8859

文摘

Fetal membranes are essential for the maintenance of sterile intrauterine milieu for proper fetal growth and development. Chronic infection and inflammation may lead to progressive stretching, hardening of the membranes, making them less elastic and more susceptible to premature rupture of membranes (PROM). PROM is associated with fetal morbidity and mortality which is inversely proportional to the period of gestation. Amniopatch even though still in experimental stages to be an established treatment for PROM, is a formidable treatment modality which has shown to seal the chorioamniotic leak and prolonging the pregnancy with improved fetal outcome. With increasing intrauterine fetal interventions both diagnostic (amniocentesis) and therapeutic (fetoscopy), amniopatch is an option for persistent amniotic fluid leakage which has shown to effectively seal the chorioamniotic leak in about two-third of the cases. Keywords Hardening Elastic Rupture Amniopatch Fetoscopy