Spectral analysis of Delayed Luminescence from human skin as a possible non-invasive diagnostic tool

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• 作者：Luca Lanzanò ; Agata Scordino ; Simona Privitera ; Salvatore Tudisco and Francesco Musumeci
• 关键词：Laser induced luminescence detection ; In vivo skin measurements ; Aging effects
• 刊名：European Biophysics Journal
• 出版年：2007
• 出版时间：September, 2007
• 年：2007
• 卷：36
• 期：7
• 页码：823-829
• 全文大小：265 KB
• 刊物类别：Physics and Astronomy
• 刊物主题：Physics
  Biophysics and Biomedical Physics
  Cell Biology
  Biochemistry
  Plant Physiology
  Animal Physiology
  Neurobiology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-1017

文摘

In vivo measurements of Delayed Luminescence (DL), the low-level photo-induced emission which lasts for a longer time after switching off the excitation light, have been performed on human skin, with the aim to develop a technique for optical biopsy. Preliminary tests have been performed on healthy volunteers, measuring the time decays of the spectral components (λ_emiss = 400–800 nm) starting 10 μs after switching off the excitation (λ_exc = 337 nm). Significant differences in the decay trends of DL from different subjects were revealed and quite a good reproducibility for the same subject was observed. The modeling of experimental data has been examined in detail in order to get parameters, characterizing the theoretical fit, whose changes may be correlated with age differences and seasonal variations.