An analysis of spine fusion outcomes in sheep pre-clinical models

详细信息    查看全文

• 作者：Emily M. Lindley ; Cameron Barton ; Thomas Blount…
• 关键词：Sheep ; Ovine ; Spine ; Fusion ; Lumbar
• 刊名：European Spine Journal
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：26
• 期：1
• 页码：228-239
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Surgical Orthopedics; Neurosurgery;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-0932
• 卷排序：26

文摘

PurposeThe ovine model is often used to evaluate new spine fusion technologies prior to clinical testing. An important aspect of designing sheep surgery protocols is to select the appropriate postoperative time period for comparing fusion outcomes. Unfortunately, determining the ideal study endpoint is complicated by the fact that prior published studies have not used consistent timeframes. Thus, the primary aim of this study was to provide a reference for investigators as to the expected fusion outcomes of control groups at varying timepoints in sheep spine surgery models.