Chromosome region 2p25 is linked and associated with type 1 diabetes in Colombia
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  • 作者:Nicolas Pineda-Trujilo (1) (7)
    Federico Uribe (2)
    Fabiola Montoya (4)
    Juan-Manuel Alfaro (1) (2)
    Guillermo Latorre (2)
    Alberto Villegas (2)
    Javier Ceron (2) (3)
    Andres-Felipe Perez (2) (3)
    Mariano Ospina (3)
    Andres Naranjo (3)
    Abel Serrano (1)
    Ivan Duque (2) (5)
    Debora Castrillon (5)
    Alberto Abad (6)
    Gabriel Bedoya (3)
    Vital Balthazar (1) (2)
    Andres Ruiz-Linares (3) (7)
  • 关键词:type 1 diabetes ; linkage ; association ; novel locus ; susceptibility locus ; Mendelian ; like
  • 刊名:Journal of Genetics
  • 出版年:2010
  • 出版时间:December 2010
  • 年:2010
  • 卷:89
  • 期:4
  • 页码:457-461
  • 全文大小:223KB
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    2. Bikker H., Vulsma T., Baas F. and de Vijlder J. J. 1995 Identification of five novel inactivating mutations in the human thyroid peroxidase gene by denaturing gradient gel electrophoresis. / Hum. Mutat. 6, 9鈥?6. CrossRef
    3. Chang C. C., Huang C. N. and Chuang L. M. 1998 Autoantibodies to thyroid peroxidase in patients with type 1 diabetes in Taiwan. / Eur. J. Endocrinol. 139, 44鈥?8. CrossRef
    4. Chistiakov D. A. and Turakulov R. I. 2003 CTLA-4 and its role in autoimmune thyroid disease. / J. Mol. Endocrinol. 31, 21鈥?6. CrossRef
    5. Donner H., Rau H., Walfish P. G., Braun J., Siegmund T., Finke R. / et al. 1997 CTLA4 alanine-17 confers genetic susceptibility to Grave鈥檚 disease and to type 1 diabetes mellitus. / J. Clin. Endocrinol. Metab. 82, 143鈥?46. CrossRef
    6. Field L. L. 2002 Genetic linkage and association studies of type I diabetes: challenges and rewards. / Diabetologia 45, 21鈥?5. CrossRef
    7. Ide A., Kawasaki E., Abiru N., Sun F., Kobayashi M., Fukushima T. / et al. 2004 Association between / IL-18 gene promoter polymorphisms and / CTLA-4 gene 49A/G polymorphism in Japanese patients with type 1 diabetes. / J. Autoimmun. 22, 73鈥?8. CrossRef
    8. Kikuoka N., Sugihara S., Yanagawa T., Ikezaki A., Kim H. S., Matsuoka H. / et al. 2001 Cytotoxic T lymphocyte antigen 4 gene polymorphism confers susceptibility to type 1 diabetes in Japanese children: analysis of association with HLA genotypes and autoantibodies. / Clin. Endocrinol. 55, 597鈥?03. CrossRef
    9. Lathrop G. M., Lalouel J. M., Julier C. and Ott J. 1984 Strategies for multilocus linkage analysis in humans. / Proc. Natl. Acad. Sci. USA 81, 3443鈥?446. CrossRef
    10. Montoya F., Bedoya C., Restrepo M., Villegas A., Posada S., Garcia H. and Vicario J. 1996 Determinacion de Marcadores geneticos en pacientes con diabetes tipo 1 y poblacion sana. / Acta Med. Colombiana 21, 1鈥?.
    11. Nagamine K., Peterson P., Scott H. S., Kudoh J., Minoshima S., Heino M. / et al. 1997 Positional cloning of the / APECED gene. / Nat. Genet. 17, 393鈥?98. CrossRef
    12. Naluai A. T., Nilsson S., Samuelsson L., Gudjonsdottir A. H., Ascher H., Ek J. / et al. 2000 The / CTLA4/ / CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders. / Tissue Antigens 56, 350鈥?55. CrossRef
    13. Pugliese A. 1999 Unraveling the genetics of insulin-dependent type 1A diabetes: the search must go on. / Diabetes Rev. 7, 77鈥?2.
    14. ROEC 2000 Report of the expert committee on the diagnosis and classification of diabetes mellitus. / Diabetes Care 1, 4鈥?9.
    15. Roivainen M., Knip M., Hyoty H., Kulmala P., Hiltunen M., Vahasalo P. / et al. 1998 Several different enterovirus serotypes can be associated with prediabetic autoimmune episodes and onset of overt IDDM. Childhood diabetes in Finland (DiMe) study group. / J. Med. Virol. 56, 74鈥?8. CrossRef
    16. Smyth D., Cooper J. D., Collins J. E., Heward J. M., Franklyn J. A., Howson J. M. / et al. 2004 Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. / Diabetes 53, 3020鈥?023. CrossRef
    17. Sobel E. and Lange K. 1996 Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. / Am. J. Hum. Genet. 58, 1323鈥?337.
    18. Spielman R. S., McGinnis R. E. and Ewens W. J. 1993 Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). / Am. J. Hum. Genet. 52, 506鈥?16.
    19. Uribe F., Pineda-Trujillo N., Montoya F., Latorre G., Villegas A., Ceron J. / et al. 2004 Analisis de ligamiento genetico de la diabetes mellitus tipo 1 a marcadores de los cromosomas 2 y 11 en familias antioque帽as. / IATREIA 17, 93鈥?04.
    20. Verge C. F., Vardi P., Babu S., Bao F., Erlich H. A., Bugawan T. / et al. 1998 Evidence for oligogenic inheritance of type 1 diabetes in a large Bedouin Arab family. / J. Clin. Invest. 102, 1569鈥?575. CrossRef
  • 作者单位:Nicolas Pineda-Trujilo (1) (7)
    Federico Uribe (2)
    Fabiola Montoya (4)
    Juan-Manuel Alfaro (1) (2)
    Guillermo Latorre (2)
    Alberto Villegas (2)
    Javier Ceron (2) (3)
    Andres-Felipe Perez (2) (3)
    Mariano Ospina (3)
    Andres Naranjo (3)
    Abel Serrano (1)
    Ivan Duque (2) (5)
    Debora Castrillon (5)
    Alberto Abad (6)
    Gabriel Bedoya (3)
    Vital Balthazar (1) (2)
    Andres Ruiz-Linares (3) (7)

    1. Mapeo Genetico, Departamento de Pediatria, Universidad de Antioquia, Cra 51 D# 62-29, AA 1226, Medellin, Colombia
    7. The Galton Laboratory, Department of Biology (Wolfson House), University College London, London, UK
    2. Endocrinologia y Metabolismo, Departamento de Medicina Interna, Universidad de Antioquia, Cra 51 D# 62-29, AA 1226, Medellin, Colombia
    4. Facultad de Medicina, Pontificia Universidad Bolivariana, Bucaramanga, Colombia
    3. GENMOL, Universidad de Antioquia, Cra 51 D# 62-29, AA 1226, Medellin, Colombia
    5. Hospital Universitario San Vicente de Pa煤l, Cochabamba, Bolivia
    6. Laboratorio de Endocrinologia, Cra 51 D# 62-29, AA 1226, Medellin, Colombia
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