Glottic-SubGlottic adenoid cystic carcinoma. A case report and review of the literature

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• 作者：Domenico Testa (120)
  Germano Guerra (121)
  Giovanni Conzo (122)
  Michele Nunziata (120)
  Gioacchino D’Errico (120)
  Maria Siano (123)
  Gennaro Ilardi (123)
  Mario Vitale (124)
  Francesco Riccitiello (125)
  Gaetano Motta (120)
  
• 刊名：BMC Surgery
• 出版年：2013
• 出版时间：October 2013
• 年：2013
• 卷：13
• 期：2-supp
• 全文大小：
• 作者单位：Domenico Testa (120)
  Germano Guerra (121)
  Giovanni Conzo (122)
  Michele Nunziata (120)
  Gioacchino D’Errico (120)
  Maria Siano (123)
  Gennaro Ilardi (123)
  Mario Vitale (124)
  Francesco Riccitiello (125)
  Gaetano Motta (120)
  
  120. Department of Otolaryngology, Head and Neck Surgery, Second University of Naples, Naples, Italy
  121. Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy
  122. Department of Anesthesiology, Surgery and Emergency, Second University of Naples, Naples, Italy
  123. Department of Advanced Biomedical Science, Unit of Pathology, University of Naples “Federico II”, Naples, Italy
  124. Department of Medicine and Surgery, University of Salerno, Baronissi (SA), Italy
  125. Department of Neuroscience and Reproductive and Dentistry Sciences, University of Naples “Federico II”, Naples, Italy
  
• ISSN：1471-2482

文摘

Background Malignant tumours of minor salivary glands are uncommon, representing only 2-4% of all head and neck cancers. In the larynx, minor salivary gland tumours rarely occur and constitute less than 1% of laryngeal neoplasm. Most of the minor salivary gland tumours arise in the subglottis; however, they can also occur in the supraglottis, in the false vocal cords, aryepiglottic folds and caudal portion of the epiglottis. The most common type of malignant minor salivary gland tumour is adenoid cystic carcinoma. Methods We present a unusual case of adenoid cystic carcinoma of glottic-subglottic region in a 61-year-old woman. Follow-up endoscopy and laryngeal magnetic resonance imaging (MRI) at three years after treatment showed no recurrence of the tumour. Results The diagnosis of glottic-subglottic adenoid cystic carcinoma should be considered in patients who are characterized by dyspnea, cough and stridor, but do not respond to pharmacologic approach. Conclusions Adenoid cystic carcinoma is usually a very slow growing cancer, invested by an apparently normal laryngeal mucosa, so that it can show no clear symptoms for a long time. For these reasons the increasing number of diagnostic mistakes or late diagnosis that may be fatal in some cases.