Antioxidant capacities of the selenium nanoparticles stabilized by chitosan

详细信息    查看全文

• 作者：Xiaona Zhai ; Chunyue Zhang ; Guanghua Zhao ; Serge Stoll…
• 关键词：Chitosan ; Selenium nanoparticles ; ROS ; Lipofuscin ; UV radiation ; d ; Galactose
• 刊名：Journal of Nanobiotechnology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：15
• 期：1
• 全文大小：2172KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Biotechnology; Nanotechnology; Molecular Medicine;
• 出版者：BioMed Central
• ISSN：1477-3155
• 卷排序：15

文摘

BackgroundsSelenium (Se) as one of the essential trace elements for human plays an important role in the oxidation reduction system. But the high toxicity of Se limits its application. In this case, the element Se with zero oxidation state (Se0) has captured our attention because of its low toxicity and excellent bioavailability. However, Se0 is very unstable and easily changes into the inactive form. By now many efforts have been done to protect its stability. And this work was conducted to explore the antioxidant capacities of the stable Se0 nanoparticles (SeNPs) stabilized using chitosan (CS) with different molecular weights (Mws) (CS-SeNPs).