An unusual association of a sellar gangliocytoma with a prolactinoma

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• 作者：Omar Serri ; France Berthelet ; Manon Bélair ; Sophie Vallette and Sylvia L. Asa
• 关键词：Prolactinoma ; Gangliocytoma ; Pituitary
• 刊名：Pituitary
• 出版年：2008
• 出版时间：March, 2008
• 年：2008
• 卷：11
• 期：1
• 页码：85-87
• 全文大小：235.1 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Diabetes
  Neurosurgery
  
• 出版者：Springer Netherlands
• ISSN：1573-7403

文摘

The simultaneous occurrence of a hypothalamic and sellar gangliocytoma with a pituitary prolactinoma is very rare. The explanation for such an association is not known. We describe the case of a woman who had a coexisting adjacent pituitary prolactinoma and gangliocytoma within the same sellar mass. The tumor cells of the gangliocytoma demonstrated expression of enkephalin, a product of proopiomelanocortin known to be a prolactin secretagogue. We postulate that in this patient there may be a link between gangliocytoma enkephalin and prolactin hypersecretion.