Prenatal renal vein thrombosis in dichorionic twin pregnancy

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• 作者：Sarah K. Weber (1)
  Andreas Müller (2)
  Annegret Geipel (1)
  Christoph Berg (1)
  Ulrich Gembruch (1)
  
• 关键词：Renal vein thrombosis ; Hyperechogenic kidney ; Hydrops ; Fetus ; Prenatal diagnosis
• 刊名：Archives of Gynecology and Obstetrics
• 出版年：2014
• 出版时间：September 2014
• 年：2014
• 卷：290
• 期：3
• 页码：587-590
• 全文大小：363 KB
• 参考文献：1. Oppenheimer EH, Esterly JR (1965) Thrombosis in the newborn: comparison between infants of diabetic and non diabetic mothers. J Pediatr 67:549-56 CrossRef
  2. Brand?o LR, Simpson EA, Lau KK (2011) Neonatal renal vein thrombosis. Semin Fetal Neonatal Med 16:323-28 CrossRef
  3. B?kenkamp A, von Kries R, Nowak-G?ttl U, G?bel U, Hoyer PF (2000) Neonatal renal venous thrombosis in Germany between 1992 and 1994: epidemiology, treatment and outcome. Eur J Pediatr 159:44-8 CrossRef
  4. Winyard PJD, Bharucha T, de Bruyn R, Dillon MJ, van’t Hoff W, Trompeter RS, Liesner R, Wade A, Rees L (2006) Perinatal renal venous thrombosis: presenting renal length predicts outcome. Arch Dis Child Fetal Neonatal Ed 91:F273–F278 CrossRef
  5. Kosch A, Kuwertz-Broking E, Heller C, Kurnik K, Schobess R, Nowak-G?ttl U (2004) Renal venous thrombosis in neonates: prothrombotic risk factors and long-term follow-up. Blood 104:1356-360 CrossRef
  6. Heller C, Schobess R, Kurnik K, Junker R, Günther G, Kreuz W, Nowak-G?ttl U (2000) Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors: a multicenter case control study, for the childhood thrombophilia study group. Br J Haematol 111:534-39 CrossRef
  7. Weissmann-Brenner A, Ferber A, O’Reilly-Green C, Avila C, Grassi A, Divon MY (2004) Inferior vena cava thrombosis presenting as non-immune hydrops in the fetus of a women with diabetes. Ultrasound Obstet Gynecol 23(2):194-97 CrossRef
  8. Hage ML, LIU R, Marcheschi DG, Bowie JD, Allen NB, Macik BG (1994) Fetal renal vein thrombosis, hydrops fetalis and maternal lupus anticoagulant: a case report. Prenat Diagn 14:873-77 CrossRef
  9. Smorgick N, Herman A, Wiener Y, Halperin R, Sherman D (2007) Prenatal thrombosis of the inferior vena cava and the renal veins. Prenatal Diagn 27:603-07 CrossRef
  10. Diallo A, Boog GJ, Moussally F, Quere MP (1998) Fetal renal venous thrombosis: a typical ultrasonographic aspect. J Gynecol Obstet Biol Reprod (Paris) 27:445-47
  11. Sanders LD, Jequier S (1989) Ultrasound demonstration of prenatal renal vein thrombosis. Pediatr Radiol 19:133-35 CrossRef
  12. Patel RB, Connors JJ (1988) In utero sonographic findings in fetal renal vein thrombosis with calcifications. J Ultrasound Med 7:349-52
  13. Stanek J, Bove KE, Bofinger M, Needham D, Saldana LR, Mutema GK, Meyer R (2000) Premature closure of foramen ovale and renal vein thrombosis in a stillborn twin homozygous for methylene tetrahydrofolate reductase gene polymorphism: a clinicopathologic case study. J Perinat Med 28:61-8 CrossRef
  14. Lau KK, Fernandez y Garcia E, Kwan WY, Albrecht L, Stein-Wexler R (2007) Bilateral renal venous thrombosis and adrenal hemorrhage: sequential prenatal US with postnatal recovery. Pediatr Radiol 37:912-15 CrossRef
  15. Prelog M, Fischer H, Gassner I, Tzankov A, Glatz-Krieger K, Mihatsch M, Zimmerhackl LB (2006) Bilateral renal vein thrombosis in a twin newborn without known risk factors. Clin Nephrol 66:135-39 CrossRef
  16. Kuhle S, Massicotte P, Chan A, Mitchell L (2004) A case series of 72 neonates with renal vein thrombosis: data from the 1-800-NO-CLOTS registry. Thromb Haemost 92:729-33
  
• 作者单位：Sarah K. Weber (1)
  Andreas Müller (2)
  Annegret Geipel (1)
  Christoph Berg (1)
  Ulrich Gembruch (1)
  
  1. Department of Obstetrics and Prenatal Medicine, University of Bonn, Sigmund-Freud Str 25, 53105, Bonn, Germany
  2. Department of Neonatology, University of Bonn, Bonn, Germany
  
• ISSN：1432-0711

文摘

Background Prenatal renal vein thrombosis is a rarely described diagnostic finding. The etiology is unclear in the majority of cases, although thrombophilia was found in some affected fetuses. Precise ultrasound scan can improve detection rate of neonatal thrombosis due to characteristic findings. Case report We present the unusual case of a dichorionic twin pregnancy in 31?weeks of gestation with one affected fetus, showing already intrauterine a bilaterally enlarged kidney and absence of renal venous flow. Additionally, the fetus showed signs of circulatory compromise and fetal distress, while dichorionic male co-twin was healthy. The postnatal thrombophilia investigations revealed a heterozygous factor V Leiden mutation. Conclusion Fetal renal vein thrombosis may occur bilateral and may also involve the inferior vena cava. Rapid deterioration of fetal condition, abnormal fetal Doppler, appearance of hydrops fetalis, may accompany fetal venous thrombosis. By color Doppler flow mapping abnormal arterial and absent venous perfusion of the affected kidney may be demonstrated in addition.