The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China

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• 作者：Ziqin Dian ; Mao Fan ; Binghui Wang ; Yue Feng ; Hao Ji ; Shuwei Dong…
• 关键词：Rotavirus A ; Children ; Gastroenteritis ; Epidemiology ; Genotype
• 刊名：Archives of Virology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：162
• 期：1
• 页码：281-285
• 全文大小：1071KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Virology; Medical Microbiology; Infectious Diseases;
• 出版者：Springer Vienna
• ISSN：1432-8798
• 卷排序：162

文摘

The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections.