Pauci-immune crescentic glomerulonephritis associated with use of trimethoprim–sulfamethoxazole
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- 作者：Shruti S. Hegde ; Vanesa Bijol ; Bertrand L. Jaber
- 关键词：Trimethoprim–sulfamethoxazole ; Rapidly progressive glomerulonephritis ; Pauci ; immune crescentic glomerulonephritis
- 刊名：CEN Case Reports
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：5
- 期：2
- 页码：188-191
- 全文大小：
- 刊物主题：Nephrology; Urology;
- 出版者：Springer Japan
- ISSN：2192-4449
- 卷排序：5
文摘
Drug-induced pauci-immune crescentic glomerulonephritis has been described with several agents, including propylthiouracil, minocycline, d-penicillamine, and hydralazine. We present the case of a 60-year-old man who presented with rapidly progressive glomerulonephritis in the setting of recent use of trimethoprim–sulfamethoxazole complicated by the development of the Stevens–Johnson syndrome, and was found to have biopsy-proven pauci-immune crescentic glomerulonephritis and undetectable anti-neutrophilic cytoplasmic antibodies. We review the existing literature on the potential association between sulfonamides and hypersensitivity polyangiitis.