Death from pulmonary embolism of cyanoacrylate glue following gastric varix endoscopic injection

详细信息    查看全文

• 作者：Michael Philip Burke ; Chris O’Donnell…
• 关键词：Cyanoacrylate ; Glue ; Pulmonary embolism
• 刊名：Forensic Science, Medicine, and Pathology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：13
• 期：1
• 页码：82-85
• 全文大小：
• 刊物主题：Pathology; Forensic Medicine; Criminology and Criminal Justice, general;
• 出版者：Springer US
• ISSN：1556-2891
• 卷排序：13

文摘

We present the case of a 25 year old woman with a complex past medical history including Crigler-Najjar syndrome (Type 1) with a liver transplant in 1993 and subsequent development of cirrhosis with portal hypertension in the transplanted liver. The deceased presented to hospital with hematemesis and investigations showed a large gastric varix. The varix was injected with cyanoacrylate glue. Within 30 min of injection the patient became acutely hypoxic. Urgent chest X-ray demonstrated radio opaque glue within the pulmonary arteries. It was evident that future treatment was futile and supportive treatment was withdrawn. The deceased was referred for medico legal post mortem examination. The post mortem CT scan performed prior to autopsy showed widespread radio-opaque material within the pulmonary arteries. At autopsy, rubbery grey/tan “clot” occluded the major proximal and segmental pulmonary arteries. Microscopic examination of the “clot” showed clumps of erythrocytes surrounded by foreign material. We discuss this relatively uncommon but well recognized complication of variceal injection with cyanoacrylate glue.