Architectures of Multivalent Glycomimetics for Probing CarbohydrateCLectin Interactions

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• 作者：Martina Lahmann
• 关键词：Carbohydrate– ; lectin interaction ; Chemoselective ligation ; Conjugation technique ; Glycocluster ; Glycoconjugate ; Glycodendrimer ; Multivalency
• 刊名：Topics in Current Chemistry
• 出版年：2009
• 出版时间：2009
• 年：2009
• 卷：288
• 期：1
• 页码：17-65
• 全文大小：1.5 MB

文摘

Well-defined multivalent glycoconjugates are valued tools in glycoscience and they are particularly valuable for the investigation of carbohydrate–lectin interactions. In addition to the relatively globularly shaped glycodendrimers many other designs have been realized. This chapter gives an overview on the common different architectures and their chemical synthesis by focussing on the achievements made since 2001.