1. Klinik für Viszeral-, Transplantations-, Thorax- und Gef??chirurgie, Universit?tsklinikum Leipzig, Liebigstra?e 20, 04103, Leipzig, Deutschland 2. Klinik und Poliklinik für Allgemein-, Viszeral- und Tumorchirurgie, Universit?tsklinik K?ln, K?ln, Deutschland
ISSN:1433-0415
文摘
Context Surgery for esophageal cancer is the mainstay of curative therapy. The standard procedure for carcinomas of the middle and distal esophagus at present is transthoracic en bloc esophagectomy in combination with reconstruction by gastric pull-up and high intrathoracic esophagogastrostomy (so-called Ivor Lewis resection). Method Research and analysis of the current literature. Results Transthoracic en bloc esophagectomy routinely includes a two field lymph node dissection. There exists a clear correlation between the extent of lymphadenectomy and the prognosis. The abdominal as well as the thoracic part of the procedure can be managed by minimally invasive or hybrid technique. Selection of patients and preoperative risk analysis are of special significance before surgery. There is a close link between the preoperative risk and the postoperative course. In addition, clinical volume and surgeons-case experience decisively influence the perioperative and oncological results. A current meta-analysis did not show an increased risk of postoperative complications after neoadjuvant chemotherapy or radiochemotherapy compared with surgery alone.