K-t GRAPPA-accelerated 4D flow MRI of liver hemodynamics: influence of different acceleration factors on qualitative and quantitative assessment of blood flow

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• 作者：Zoran Stankovic ; Jury Fink…
• 关键词：4D flow MRI ; Liver hemodynamics ; k ; t GRAPPA ; Quantification ; Wall shear stress
• 刊名：Magnetic Resonance Materials in Physics, Biology and Medicine
• 出版年：2015
• 出版时间：April 2015
• 年：2015
• 卷：28
• 期：2
• 页码：149-159
• 全文大小：912 KB
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  14. Stankovic, Z, Csatari, Z, Deibert, P, Euringer, W, Blanke, P, Kreisel, W, Abdullah Zadeh, Z, Kallfass, F, Langer, M, Markl, M (2012) Normal and altered three-dimensional portal venous hemodynamics in patients with liver cirrhosis. Radiology 262: pp. 862-873 CrossRef
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• 刊物主题：Imaging / Radiology; Computer Appl. in Life Sciences; Solid State Physics; Biomedical Engineering; Health Informatics;
• 出版者：Springer Berlin Heidelberg
• ISSN：1352-8661

文摘

Objective We sought to evaluate the feasibility of k-t parallel imaging for accelerated 4D flow MRI in the hepatic vascular system by investigating the impact of different acceleration factors. Materials and methods k-t GRAPPA accelerated 4D flow MRI of the liver vasculature was evaluated in 16 healthy volunteers at 3T with acceleration factors R?=?3, R?=?5, and R?=?8 (2.0?×?2.5?×?2.4?mm3, TR?=?82?ms), and R?=?5 (TR?=?41?ms); GRAPPA R?=?2 was used as the reference standard. Qualitative flow analysis included grading of 3D streamlines and time-resolved particle traces. Quantitative evaluation assessed velocities, net flow, and wall shear stress (WSS). Results Significant scan time savings were realized for all acceleration factors compared to standard GRAPPA R?=?2 (21-1?%) (p?R?=?3 and R?=?5 compared to standard GRAPPA R?=?2. Significantly increased leakage artifacts and noise were seen between standard GRAPPA R?=?2 and k-t GRAPPA R?=?8 (p?p?R?=?5, while significantly higher values were observed for the same acceleration with higher temporal resolution in two veins (p? Conclusion k-t acceleration of 4D flow MRI is feasible for liver hemodynamic assessment with acceleration factors R?=?3 and R?=?5 resulting in a scan time reduction of at least 40?% with similar quantitation of liver hemodynamics compared with GRAPPA R?=?2.