Application of Ionic Liquid-Based Ultrasound-Assisted Extraction of Five Phenolic Compounds from Fig (Ficus carica L.) for HPLC-UV

详细信息    查看全文

• 作者：Hongying Qin ; Guangming Zhou ; Guilong Peng ; Junping Li…
• 关键词：High ; performance liquid chromatography ; Ionic liquid ; Ultrasound ; assisted extraction ; Phenolic compounds ; Ficus carica L.
• 刊名：Food Analytical Methods
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：8
• 期：7
• 页码：1673-1681
• 全文大小：387 KB
• 参考文献：Aghel N, Kalantari H, Rezazadeh S (2011) Effect of Ficus carica leaf extract on mice intoxicated with carbon tetrachloride. Iran J Pharm Res 10:63-7
  Barros F, Dykes L, Awika JM, Rooney LW (2013) Accelerated solvent extraction of phenolic compounds from sorghum brans. J Cereal Sci 58:305-12View Article
  Bey MB, Louaileche H, Zemouri S (2013) Optimization of phenolic compound recovery and antioxidant activity of light and dark dried fig (Ficus carica L.) varieties. Food Sci Biotechnol 22:1613-619View Article
  Bhat MZA, Ali DM, Mir SR (2013) Anti-diabetic activity of Ficus carica L. stem barks and isolation of two new flavonol esters from the plant by using spectroscopical techniques. Asian J Biomed Pharm Sci 3:22-8
  Canal JR, Torres MD, Romero A, Pérez C (2000) A chloroform extract obtained from a decoction of Ficus carica leaves improves the cholesterolaemic status of rats with streptozotocin-induced diabetes. Acta Physiol Hung 87:71-6View Article
  Caro AD, Piga A (2008) Polyphenol composition of peel and pulp of two Italian fresh fig fruits cultivars (Ficus carica L.). Eur Food Res Technol 226:715-19View Article
  Chi CY, Shi B, Liang P, Li JM, Yoichiro I (2009) Isolation and purification of psoralen and bergapten from Ficus carica L. leaves by high-speed countercurrent chromatography. J Liq Chromatogr Relat Technol 32:136-43
  Chun S, Dzyuba SV, Bartsch RA (2001) Influence of structural variation in room-temperature ionic liquids on the selectivity and efficiency of competitive alkali metal salt extraction by a crown ether. Anal Chem 73:3737-741View Article
  Conforti F, Menichini G, Zanfini L, Tundis R, Statti GA, Provenzano E, Menichini F, Somma F, Alfano C (2012) Evaluation of phototoxic potential of aerial components of the fig tree against human melanoma. Cell Prolif 45:279-85View Article
  Guo Z, Lue BM, Thomasen K, Meyer AS, Xu XB (2007) Predictions of flavonoid solubility in ionic liquids by COSMO-RS: experimental verification, structural elucidation, and solvation characterization. Green Chem 9:1362-373View Article
  Jagathambal M, Madhavan K, Parvathi V, Karunakaran G (2011) Phytochemical screening and antimicrobial activity of seven solvent extracts of dried fruit of Ficus carica against five human pathogenic bacteria. J Pharm Res 4:4498
  Jeong WS, Lachance PA (2001) Phytosterols and fatty acids in fig (Ficus carica, var. Mission) fruit and tree components. J Food Sci 66:278-81View Article
  Konyalιog?lu S, Sag?lam H, Kιvak B (2005) α-Tocopherol, flavonoid, and phenol contents and antioxidant activity of Ficus carica leaves. Pharm Biol 43:683-86View Article
  Liang P, Wang F, Wan Q (2013) Ionic liquid-based ultrasound-assisted emulsification microextraction coupled with high performance liquid chromatography for the determination of four fungicides in environmental water samples. Talanta 105:57-2View Article
  Meric S, Gulum S, Serpil S (2012) Microwave assisted extraction of phenolic compounds from sour cherry pomace. Sep Sci Technol 47:1248-254View Article
  Mu?iz-Márquez DB, Martínez-ávila GC, Wong-Paz JE, Belmares-Cerda R, Rodríguez-Herrera R, Aguilar CN (2013) Ultrasound-assisted extraction of phenolic compounds from Laurus nobilis L. and their antioxidant activity. Ultrason Sonochem 20:1149-154View Article
  Orhan IE, Ustün O, Sener B (2011) Estimation of cholinesterase inhibitory and antioxidant effects of the leaf extracts of Anatolian Ficus carica var. domestica and their total phenol and flavonoid contents. Nat Prod Commun 6:375-78
  Pande G, Akoh CC (2010) Organic acids, antioxidant capacity, phenolic content and lipid characterization of georgia-grown underutilized fruit crops. Food Chem 120:1067-075View Article
  Rubnov S, Kashman Y, Rabinowitz R, Schlesinger M, Mechoulam R (2001) Suppressors of cancer cell proliferation from fig (Ficus carica) resin: isolation and structure elucidation. J Nat Prod 64:993View Article
  Santos DT, Veggi PC, Meireles MAA (2012a) Optimization and economic evaluation of pressurized liquid extraction of phenolic compounds from jabuticaba skins. J Food Eng 108:444-52View Article
  Santos SAO, Villaverde JJ, Silva CM, Neto CP, Silvestre AJD (2012b) Supercritical fluid extraction of phenolic compounds from Eucalyptus globulus Labill bark. J Supercrit Fluids 71:71-9View Article
  Slatnar A, Klanca U, Stampar F, Veberic R (2011) Effect of drying of figs (Ficus carica L.) on the contents of sugars, organic acids, and phenolic compounds. J Agric Food Chem 59:11696-1702View Article
  Slavin JL (2006) Figs: past, present and future. Nutr Today 41:180-84View Article
  Solomon A, Golubowicz S, Yablowicz Z, Grossman S, Bergman M, Gottlieb HE, Altman A, Kerem Z, Flaishman MA (2006) Antioxidant activities and anthocyanin content of fresh fruits of common fig (Ficus carica L.). J Agric Food Chem 54:7717-723View Article
  Sun P, Armstrong DW (2010) Ionic liquids in analytical chemistry. Anal Chim
• 作者单位：Hongying Qin (1)
  Guangming Zhou (1)
  Guilong Peng (1)
  Junping Li (1)
  Junhua Chen (1)
  
  1. Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Food Science
  Chemistry
  Microbiology
  Analytical Chemistry
  
• 出版者：Springer New York
• ISSN：1936-976X

文摘

Ionic liquid-based ultrasonic-assisted extraction (IL-UAE) was successfully developed to extract the known phenolics gallic acid, chlorogenic acid, rutin, psoralen, and bergapten present in the leaves, pulps, and peels of Ficus carica L. In this work, the proposed method was evaluated in comparison with regular ultrasonic-assisted extraction in which methanol was the extractant and exhibited higher efficiency. Moreover, ionic liquids with different cations were investigated and 1-butyl-3-methylimidazole hexafluorophosphate solution was selected as the optimal extractant at concentration of 1.0?mol?L?. The corresponding extraction parameters including extraction solvent, the concentration of [BMIM][PF6], solid–liquid ratio (g?mL?), ultrasonic extraction time, and extraction temperature were optimized. The phenolics were then determined by high-performance liquid chromatography (HPLC). Under the optimized conditions, the content of gallic acid, chlorogenic acid, rutin, psoralen, and bergapten in leaves, pulps, and peels of F. carica L. was 12.67-7.16, 14.75-0.07, 107.91-22.37, 2.59-7.83, and 1.99-0.21?μg/0.1?g, respectively. This study suggests that IL-UAE is a rapid, simple, and green preparation technique.