The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast
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- 作者：Haidan Jin ; Meiying Ji ; Liyan Chen…
- 关键词：Breast cancer ; Mortalin ; Survival analysis ; Biomarker
- 刊名：Journal of Experimental & Clinical Cancer Research
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：35
- 期：1
- 全文大小：1,462 KB
- 刊物主题：Oncology; Cancer Research;
- 出版者：BioMed Central
- ISSN：1756-9966
文摘
Background Mortalin/GRP75 is a ubiquitous mitochondrial chaperone which related to the cytosolic heat shock protein 70 (HSP70), and plays a role in carcinogenesis. This study aims to investigate the Mortalin expression in breast cancer and its correlation with the outcome of the patients with breast cancer.