Harnessing microbiome and probiotic research in sub-Saharan Africa: recommendations from an African workshop
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- 作者：Gregor Reid (1)
Nicholas Nduti (2)
Wilbert Sybesma (3)
Remco Kort (3) (4)
Tobias R Kollmann (5)
Rod Adam (6)
Hamadi Boga (7)
Eric M Brown (8)
Alexandra Einerhand (9)
Hani El-Nezami (10)
Gregory B Gloor (11)
Irene I Kavere (12)
Johanna Lindahl (13)
Amee Manges (14)
Wondu Mamo (15)
Rocio Martin (9)
Amy McMillan (1)
Jael Obiero (16)
Pamela A Ochieng鈥?/a> (12)
Arnold Onyango (12)
Stephen Rulisa (17)
Eeva Salminen (18)
Seppo Salminen (19)
Antony Sije (12)
Jonathan R Swann (20)
William van Treuren (21)
Daniel Waweru (12)
Steve J Kemp (22)
1. Lawson Health Research Institute and Departments of Microbiology & Immunology ; and Surgery ; University of Western Ontario ; 268 Grosvenor Street ; London ; Ontario ; N6A 4V2 ; Canada
2. Ministry of Agriculture ; Waruhiu Agriculture training Center ; P.O. Box 800 ; Githunguri ; Kenya
3. Yoba for Life Foundation ; Hunzestraat 133-A ; 1079 WB ; Amsterdam ; The Netherlands
4. TNO Microbiology and Systems Biology ; Utrechtseweg 48 ; 3704 HE Zeist ; and Molecular Cell Physiology ; VU University ; De Boelelaan 1085 ; 1081 HV ; Amsterdam ; The Netherlands
5. Department of Pediatrics ; Division of Infectious Diseases ; University of British Columbia ; CFRI A5-147 ; 950 W28th Ave ; Vancouver ; BC ; V5Z 4H4 ; Canada
6. Department of Pathology ; Aga Khan University Hospital ; Nairobi ; Kenya
7. Taita Taveta University College ; P.O. Box 635鈥?0300 ; Voi ; Kenya
8. Michael Smith Laboratories and Department of Microbiology and Immunology ; University of British Columbia ; Vancouver ; Canada
9. Danone Nutricia Research ; Uppsalalaan 12 ; 3584 CT ; Utrecht ; The Netherlands
10. School of Biological Sciences ; University of Hong Kong ; Pokfulam Rd ; Hong Kong ; Hong Kong SAR
11. Department of Biochemistry ; University of Western Ontario ; London ; ON ; Canada
12. Jomo Kenyatta University of Agriculture and Technology ; P.O. Box 62000 ; (00200) ; Nairobi ; Kenya
13. Consultative Group on International Agricultural Research ; ILRI ; Nairobi ; Kenya
14. School of Population and Public Health ; Faculty of Medicine ; University of British Columbia ; Vancouver ; BC ; V6T 1Z3 ; Canada
15. Department of Animal Production ; College of Veterinary Medicine and Agriculture ; Addis Ababa University ; Debre Zeyte ; Ethiopia
16. Department of Reproductive Health/Biology ; Institute of Primate Research ; Karen ; Nairobi ; Kenya
17. University Teaching Hospital of Kigali ; National University of Rwanda ; Kigali ; Rwanda
18. Functional Foods Forum ; The Medical School ; University of Turku ; 20014 ; Turku ; Finland
19. Department of Oncology ; Turku University Hospital ; 20520 ; Turku ; Finland
20. Department of Food and Nutritional Sciences ; School of Chemistry ; Food and Pharmacy ; University of Reading ; Reading ; RG6 6AP ; United Kingdom
21. Department of Chemistry and Biochemistry and BioFrontiers Institute ; University of Colorado at Boulder ; Boulder ; CO ; 80309 ; USA
22. International Livestock Research Institute ; Nairobi ; Kenya - 刊名：Microbiome
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：2
- 期：1
- 全文大小：923 KB
- 参考文献：1. Lee, MH, Lee, SW (2013) Bioprospecting potential of the soil metagenome: novel enzymes and bioactivities. Genomics Inform 11: pp. 114-120 CrossRef
2. Pan, D, Yu, Z (2013) Intestinal microbiome of poultry and its interaction with host and diet. Gut Microbes 31: pp. 5
3. Brestoff, JR, Artis, D (2013) Commensal bacteria at the interface of host metabolism and the immune system. Nat Immunol 14: pp. 676-684 CrossRef
4. Yeoh, N, Burton, JP, Suppiah, P, Reid, G, Stebbings, S (2013) The role of the microbiome in rheumatic diseases. Curr Rheumatol Rep 15: pp. 314 CrossRef
5. Lozupone, CA, Stombaugh, JI, Gordon, JI, Jansson, JK, Knight, R (2012) Diversity, stability and resilience of the human gut microbiota. Nature 489: pp. 220-230 CrossRef
6. Goldenberg, JZ, Ma, SS, Saxton, JD, Martzen, MR, Vandvik, PO, Thorlund, K, Guyatt, GH, Johnston, BC (2013) Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev 5: pp. CD006095
7. Reid, G, Younes, JA, van der Mei, HC, Gloor, GB, Knight, R, Busscher, HJ (2011) Microbiota restoration: natural and supplemented recovery of human microbial communities. Nat Rev Microbiol 9: pp. 27-38 CrossRef
8. Howarth, GS, Butler, RN, Salminen, S, Gibson, GR, Donovan, SM (2012) Probiotics for optimal nutrition: from efficacy to guidelines. Adv Nutr 3: pp. 720-722 CrossRef
9. Petschow, B, Dor茅, J, Hibberd, P, Dinan, T, Reid, G, Blaser, M, Cani, PD, Degnan, FH, Foster, J, Gibson, G, Hutton, J, Klaenhammer, TR, Ley, R, Nieuwdorp, M, Pot, B, Relman, D, Serazin, A, Sanders, ME (2013) Probiotics, prebiotics, and the host microbiome: the science of translation. Ann N Y Acad Sci 1306: pp. 1-17 CrossRef
10. Hummelen, R, Fernandes, AD, Macklaim, JM, Dickson, RJ, Changalucha, J, Gloor, GB, Reid, G (2010) Deep sequencing of the vaginal microbiota of women with HIV. PLoS One 5: pp. e12078 CrossRef
11. de Filippo, C, Cavalieri, D, di Paola, M, Ramazzotti, M, Poullet, JB, Massart, S, Collini, S, Pieraccini, G, Lionetti, P (2010) Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 107: pp. 14691-14696 CrossRef
12. Tito, RY, Knights, D, Metcalf, J, Obregon-Tito, AJ, Cleeland, L, Najar, F, Roe, B, Reinhard, K, Sobolik, K, Belknap, S, Foster, M, Spicer, P, Knight, R, Lewis, CM (2012) Insights from characterizing extinct human gut microbiomes. PLoS One 7: pp. e51146 CrossRef
13. Grze艣kowiak, L, Collado, MC, Mangani, C, Maleta, K, Laitinen, K, Ashorn, P, Isolauri, E, Salminen, S (2012) Distinct gut microbiota in southeastern African and northern European infants. J Pediatr Gastroenterol Nutr 54: pp. 812-816 CrossRef
14. Gr枚nlund, MM, Grze艣kowiak, L, Isolauri, E, Salminen, S (2011) Influence of mother鈥檚 intestinal microbiota on gut colonization in the infant. Gut Microbes 2: pp. 227-233 CrossRef
15. Zimmermann, MB, Chassard, C, Rohner, F, N鈥檊oran, EK, Nindjin, C, Dostal, A, Utzinger, J, Ghattas, H, Lacroix, C, Hurrell, RF (2010) The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d鈥橧voire. Am J Clin Nutr 92: pp. 1406-1415 CrossRef
16. Mwirichia, R, Cousin, S, Muigai, AW, Boga, HI, Stackebrandt, E (2011) Bacterial diversity in the haloalkaline Lake Elmenteita, Kenya. Curr Microbiol 62: pp. 209-221 CrossRef
17. Rivera, AJ, Frank, JA, Stumpf, R, Salyers, AA, Wilson, BA, Olsen, GJ, Leigh, S (2011) Differences between the normal vaginal bacterial community of baboons and that of humans. Am J Primatol 73: pp. 119-126 CrossRef
18. Douillard, FP, Ribbera, A, Kant, R, Pietil盲, TE, J盲rvinen, HM, Messing, M, Randazzo, CL, Paulin, L, Laine, P, Ritari, J, Caggia, C, L盲hteinen, T, Brouns, SJ, Satokari, R, von Ossowski, I, Reunanen, J, Palva, A, de Vos, WM (2013) Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG. PLoS Genet 9: pp. e1003683 CrossRef
19. Wang, Y, Gilbreath, TM, Kukutla, P, Yan, G, Xu, J (2011) Dynamic gut microbiome across life history of the malaria mosquito Anopheles gambiae in Kenya. PLoS One 6: pp. e24767 CrossRef
20. Lei, V, Jakobsen, M (2004) Microbiological characterization and probiotic potential of koko and koko sour water, African spontaneously fermented millet porridge and drink. J Appl Microbiol 96: pp. 384-397 CrossRef
21. Mathara, JM, Schillinger, U, Guigas, C, Franz, C, Kutima, PM, Mbugua, SK, Shin, HK, Holzapfel, WH (2008) Functional characteristics of Lactobacillus spp. from traditional Maasai fermented milk products in Kenya. Int J Food Microbiol 126: pp. 57-64 CrossRef
22. Reid, G, Anand, S, Bingham, MO, Mbugua, G, Wadstrom, T, Fuller, R, Anukam, K, Katsivo, M (2005) Probiotics for the developing world. J Clin Gastroenterol 39: pp. 485-488 CrossRef
23. Mpofu, A, Linnemann, AR, Sybesma, W, Kort, R, Nout, MJR, Smid, E (2014) Development of a locally sustainable functional food based on mutandabota, a traditional food in Southern Africa. J Dairy Sci.
24. Hummelen, R, Changalucha, J, Butamanya, NL, Cook, A, Habbema, JD, Reid, G (2010) Lactobacillus rhamnosus GR-1 and L. reuteri RC-14 to prevent or cure bacterial vaginosis among women with HIV. Int J Gynaecol Obstet 111: pp. 245-248 CrossRef
25. Irvine, SL, Hummelen, R, Hekmat, S, Looman, CW, Habbema, JD, Reid, G (2010) Probiotic yogurt consumption is associated with an increase of CD4 count among people living with HIV/AIDS. J Clin Gastroenterol 44: pp. e201-e205 CrossRef
26. Kerac, M, Bunn, J, Seal, A, Thindwa, M, Tomkins, A, Sadler, K, Bahwere, P, Collins, S (2009) Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi. Lancet 374: pp. 136-144 CrossRef
27. M盲ndar, R (2013) Microbiota of male genital tract: impact on the health of man and his partner. Pharmacol Res 69: pp. 32-41 CrossRef
28. van Helden, PD, van Helden, LS, Hoal, EG (2013) One world, one health. Humans, animals and the environment are inextricably linked - a fact that needs to be remembered and exploited in our modern approach to health. EMBO Rep 14: pp. 497-501 CrossRef
29. Kang鈥檈the, EK, Lang鈥檃, KA (2009) Aflatoxin B1 and M1 contamination of animal feeds and milk from urban centers in Kenya. Afr Health Sci 9: pp. 218-226
30. Baines, D, Sumarah, M, Kuldau, G, Juba, J, Mazza, A, Masson, L (2013) Aflatoxin, fumonisin and shiga toxin-producing Escherichia coli infections in calves and the effectiveness of Celmanax庐/Dairyman鈥檚 Choice鈩?applications to eliminate morbidity and mortality losses. Toxins (Basel) 5: pp. 1872-1895 CrossRef
31. Smith, MI, Yatsunenko, T, Manary, MJ, Trehan, I, Mkakosya, R, Cheng, J, Kau, AL, Rich, SS, Concannon, P, Mychaleckyj, JC, Liu, J, Houpt, E, Li, JV, Holmes, E, Nicholson, J, Knights, D, Ursell, LK, Knight, R, Gordon, JI (2013) Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science 339: pp. 548-554 CrossRef
32. Soave, O, Brand, CD (1991) Coprophagy in animals: a review. Cornell Vet 81: pp. 357-364
33. Turnbaugh, PJ, Ley, RE, Hamady, M, Fraser-Liggett, CM, Knight, R, Gordon, JI (2007) The human microbiome project. Nature 449: pp. 804-810 CrossRef
34. Zheng, X, Xie, G, Zhao, A, Zhao, L, Yao, C, Chiu, NH, Zhou, Z, Bao, Y, Jia, W, Nicholson, JK, Jia, W (2011) The footprints of gut microbial-mammalian co-metabolism. J Proteome Res 10: pp. 5512-5522 CrossRef
35. di Bella, J, Bao, Y, Gloor, GB, Burton, JP, Reid, G (2013) High throughput sequencing methods and analysis for microbiome research. J Microbiol Methods 95: pp. 401-414 CrossRef
36. Seale, AC, Mwaniki, M, Newton, CR, Berkley, JA (2009) Maternal and early onset neonatal bacterial sepsis: burden and strategies for prevention in sub-Saharan Africa. Lancet Infect Dis 9: pp. 428-438 CrossRef
37. Panigrahi, P, Parida, S, Pradhan, L, Nanda, N, Satpathy, R, Chandel, D, Chaudhry, R, Misra, P, Chen, H, Johnson, JA, Morris, JG, Paneth, N, Gewolb, IH (2013) Effectiveness of a Lactobacillus plantarum synbiotic therapy for preventing late onset sepsis in neonates. Pediatric Academic Society, Vancouver
38. Panigrahi, P, Parida, S, Pradhan, L, Mohapatra, SS, Misra, PR, Johnson, JA, Chaudhry, R, Taylor, S, Hansen, NI, Gewolb, IH (2008) Long-term colonization of a Lactobacillus plantarum synbiotic preparation in the neonatal gut. J Pediatr Gastroenterol Nutr 47: pp. 45-53 CrossRef
39. Kort, R, Sybesma, W (2012) Probiotics for everybody. Trends Biotechnol 30: pp. 613-615 CrossRef
40. Manzoni, P, Lista, G, Gallo, E, Marangione, P, Priolo, C, Fontana, P, Guardione, R, Farina, D (2011) Routine Lactobacillus rhamnosus GG administration in VLBW infants: a retrospective, 6-year cohort study. Early Hum Dev 87: pp. S35-S38 CrossRef
41. Laitinen, K, Kalliom盲ki, M, Poussa, T, Lagstr枚m, H, Isolauri, E (2005) Evaluation of diet and growth in children with and without atopic eczema: follow-up study from birth to 4聽years. Br J Nutr 94: pp. 565-574 CrossRef
42. Szajewska, H, Kotowska, M, Mrukowicz, JZ, Arma艅ska, M, Miko艂ajczyk, W (2001) Efficacy of Lactobacillus GG in prevention of nosocomial diarrhea in infants. J Pediatr 138: pp. 361-365 CrossRef
43. Anukam, KC, Reid, G (2009) African traditional fermented foods and probiotics. J Medicinal Food 12: pp. 1177-1184 CrossRef
44. Franz CMAP, Huch M, Mathara JM, Abriouel H, Benomar N, Reid G, Galvez A, Holzapfel WH: The quest for probiotic African fermented foods. Manuscript submitted. / Int J Food Microbiol accepted as far as I know
45. Wirf盲lt, E, Mattisson, I, Gullberg, B, Olsson, H, Berglund, G (2005) Fat from different foods show diverging relations with breast cancer risk in postmenopausal women. Nutr Cancer 53: pp. 135-143 CrossRef
46. Larsson, SC, Andersson, SO, Johansson, JE, Wolk, A (2008) Cultured milk, yogurt, and dairy intake in relation to bladder cancer risk in a prospective study of Swedish women and men. Am J Clin Nutr 88: pp. 1083-1087
47. Ohashi, Y, Nakai, S, Tsukamoto, T, Masumori, N, Akaza, H, Miyanaga, N, Kitamura, T, Kawabe, K, Kotake, T, Kuroda, M, Naito, S, Koga, H, Saito, Y, Nomata, K, Kitagawa, M, Aso, Y (2002) Habitual intake of lactic acid bacteria and risk reduction of bladder cancer. Urol Int 68: pp. 273-280 CrossRef
48. Prahalad, CK, Hart, S (2002) The fortune at the bottom of the pyramid. Strategy Bus 26: pp. 2-14
49. van Tienen, A, Hullegie, YM, Hummelen, R, Hemsworth, J, Changalucha, J, Reid, G (2001) Development of a locally sustainable functional food intervention for people living with HIV in sub-Saharan Africa: laboratory testing and sensory evaluation. Beneficial Microbes 2: pp. 193-198 CrossRef
50. Kunyanga, C, Imungi, J, Okoth, M, Vadivel, V, Biesalski, HK (2012) Development, acceptability, and nutritional characteristics of a low-cost, shelf-stable supplementary food product for vulnerable groups in Kenya. Food Nutr Bull 33: pp. 43-52
51. Vijayan, P, Vijayaraj, P, Setty, PH, Hariharpura, RC, Godavarthi, A, Badami, S, Arumugam, DS, Bhojraj, S (2004) The cytotoxic activity of the total alkaloids isolated from different parts of Solanum pseudocapsicum. Biol Pharm Bull 27: pp. 528-530 CrossRef
52. Mangani, C, Maleta, K, Phuka, J, Cheung, YB, Thakwalakwa, C, Dewey, K, Manary, M, Puumalainen, T, Ashorn, P (2013) Effect of complementary feeding with lipid-based nutrient supplements and corn-soy blend on the incidence of stunting and linear growth among 6- to 18-month-old infants and children in rural Malawi. Matern Child Nutr.
53. Arimond, M, Zeilani, M, Jungjohann, S, Brown, KH, Ashorn, P, Allen, LH, Dewey, KG (2013) Considerations in developing lipid-based nutrient supplements for prevention of undernutrition: experience from the International Lipid-Based Nutrient Supplements (iLiNS) Project. Matern Child Nutr.
54. Kaput, J, van Ommen, B, Kremer, B, Priami, C, Monteiro, JP, Morine, M, Pepping, F, Diaz, Z, Fenech, M, He, Y, Albers, R, Drevon, CA, Evelo, CT, Hancock, RE, Ijsselmuiden, C, Lumey, LH, Minihane, AM, Muller, M, Murgia, C, Radonjic, M, Sobral, B, West, KP (2014) Consensus statement understanding health and malnutrition through a systems approach: the ENOUGH program for early life. Genes Nutr 9: pp. 378 CrossRef
55. Sanghvi, T, Jimerson, A, Hajeebhoy, N, Zewale, M, Nguyen, GH (2013) And young child feeding practices in different country settings. Food Nutr Bull 34: pp. S169-S180
56. Choi, BCK, Pang, T, Lin, V, Puska, P, Sherman, G, Goddard, M, Ackland, MJ, Sainsburry, P, Stachenko, S, Morrison, H, Clottey, C (2005) Can scientists and policy makers work together?. J Epidemiol Community Health 59: pp. 632-637 CrossRef
57. Li, J, McCormick, J, Bocking, A, Reid, G (2012) Probiotics for reproductive medicine. Reproduct Sci 19: pp. 235-242 CrossRef
58. Hummelen, R, Hemsworth, J, Changalucha, J, Butamanya, NL, Hekmat, S, Habbema, JDF, Reid, G (2011) Effect of micronutrient and probiotic fortified yogurt on immune-function of anti-retroviral therapy na茂ve HIV patients. Nutrients 3: pp. 897-909 CrossRef
59. Deshpande, G, Rao, S, Patole, S (2011) Progress in the field of probiotics: year 2011. Curr Opin Gastroenterol 27: pp. 13-18 CrossRef
60. Yunus, M (2007) Creating a world without poverty: social business and the future of capitalism. Public Affairs, New York, USA
61. Reid, MKE, Gough, R, Enos, M, Reid, G (2013) Social businesses in Tanzania tackling health issues of the Millennium Development Goals, one community kitchen at a time. J Social Bus 3: pp. 24-38
62. Bolognani, F, Rumney, CJ, Rowland, IR (1997) Influence of carcinogen binding by lactic acid-producing bacteria on tissue distribution and in vivo mutagenicity of dietary carcinogens. Food Chem Toxicol 35: pp. 535-545 CrossRef
63. el-Nezami, H, Kankaanp盲盲, P, Salminen, S, Ahokas, J (1998) Physicochemical alterations enhance the ability of dairy strains of lactic acid bacteria to remove aflatoxin from contaminated media. J Food Prot 61: pp. 466-468
64. Lahtinen, SJ, Haskard, CA, Ouwehand, AC, Salminen, SJ, Ahokas, JT (2004) Binding of aflatoxin B1 to cell wall components of Lactobacillus rhamnosus strain GG. Food Addit Contam 21: pp. 158-164 CrossRef - 刊物主题：Medical Microbiology; Bioinformatics; Microbial Ecology; Microbiology; Microbial Genetics and Genomics; Virology;
- 出版者：BioMed Central
- ISSN：2049-2618
文摘
To augment capacity-building for microbiome and probiotic research in Africa, a workshop was held in Nairobi, Kenya, at which researchers discussed human, animal, insect, and agricultural microbiome and probiotics/prebiotics topics. Five recommendations were made to promote future basic and translational research that benefits Africans.