Unprotected left main coronary artery disease

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• 作者：Prof. Dr. J. Cremer (1)
  J. Sch?ttler (1)
  A. Haneya (1)
  R. Petzina (1)
  G. Hoffmann (1)
  
• 关键词：Coronary artery disease ; Left main stenosis ; Coronary artery bypass surgery ; Percutaneous coronary intervention ; Guidelines ; Koronare Herzkrankheit ; Hauptstammstenose ; Koronare Bypassoperation ; Perkutane Koronarintervention ; Leitlinien
• 刊名：Herz
• 出版年：2013
• 出版时间：March 2013
• 年：2013
• 卷：38
• 期：2
• 页码：143-146
• 全文大小：322KB
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• 作者单位：Prof. Dr. J. Cremer (1)
  J. Sch?ttler (1)
  A. Haneya (1)
  R. Petzina (1)
  G. Hoffmann (1)
  
  1. Department of Cardiovascular Surgery, Universit?tsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Germany
  
• ISSN：1615-6692

文摘

Coronary artery bypass grafting (CABG) has been established as a safe concept in the treatment of unprotected left main coronary artery (ULMCA) disease and is considered the first-line treatment in current interdisciplinary guidelines. Regardless of the complexity of the lesion and the concomitant diseases, CABG is associated with excellent long-term results. Randomized controlled trials investigating the role of percutaneous coronary intervention in the setting of ULMCA lesions are frequently underpowered and suggest that, when restricted to less complex lesions, percutaneous coronary intervention is associated with results comparable to surgery. Thus, there is an urgent need for further randomized controlled trials RCTs with all-comers design to supply precise data under real-life conditions representative of the left main stem anatomy. Until then, an interdisciplinary approach to patients with ULMCA lesions is mandatory in view of the existing guidelines.