Ultrasensitive detection of aliphatic nitro-organics based on "turn-on" fluorescent sensor array

详细信息    查看全文

• 作者：Chen Wang ; Heng Zhang ; Li Tian ; Wei Zhu ; Yue Lan ; Jian Li…
• 关键词：turn ; on fluorescence ; explosive detection ; cross ; reactive sensory array
• 刊名：SCIENCE CHINA Chemistry
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：59
• 期：1
• 页码：89-94
• 全文大小：1,054 KB
• 参考文献：1 a).Thomas SW, Joly GD, Swager TM. Chem Rev, 2007, 107: 1339–1386CrossRef
  b).McQuade DT, Pullen AE, Swager TM. Chem Rev, 2000, 100: 2537–2574CrossRef
  c).Che Y, Gross DE, Huang H, Yang D, Yang X, Moore JS, Zhang L. J Am Chem Soc, 2012, 134: 4978–4982CrossRef
  d).Sanchez JC, Trogler WC. J Mater Chem, 2008, 18: 3143–3156CrossRef
  2 a).Salinas Y, Martínez-Máñez R, Marcos MD, Sancenn F, Costero AM, Parra M, Gil S. Chem Soc Rev, 2012, 41: 1261–1296CrossRef
  b).Lan A, Li K, Wu H, Olson DH, Emge TJ, Ki W, Hong M, Li J. Angew Chem Int Ed, 2009, 48: 2334–2337CrossRef
  3 a).Andrew TL, Swager TM. J Am Chem Soc, 2007, 129: 7254–7255CrossRef
  b).Pramanik S, Zheng C, Zhang X, Emge TJ, Li J. J Am Chem Soc, 2011, 133: 4153–4155CrossRef
  c).Germain ME, Knapp MJ. J Am Chem Soc, 2008, 130: 5422–5423CrossRef
  4.Zhu W, Li WN, Wang C, Cui JC, Yang HW, Jiang Y, Li GT. Chem Sci, 2013, 4: 3583–3590CrossRef
  5.Germain ME, Knapp MJ. J Am Chem Soc, 2008, 130: 5422–5423CrossRef
  6.Zhou H, Baldini L, Hong J, Wilson AJ, Hamilton AD. J Am Chem Soc, 2006, 128: 2421–2425CrossRef
  7.Buryak A, Severin K. J Am Chem Soc, 2005, 127: 3700–3701CrossRef
  8.Lim SH, Feng L, Kemling JW, Musto CJ, Suslick KS. Nat Chem, 2009, 1: 562–567CrossRef
  9 a).Freeman R, Finder T, Bahshi L, Gill R, Willner I. Adv Mater, 2012, 24: 6416–6421CrossRef
  b).Sabherwal P, Shorie M, Pathania P, Chaudhary S, Bhasin KK, Bhalla V, Suri CR. Anal Chem, 2014, 86: 7200–7204CrossRef
  c).Zou WS, Zou FH, Shao Q, Zhang J, Wang YQ, Xie FZ, Ding YJ. Photochem Photobiol A Chem, 2014, 278: 82–88CrossRef
  d).Qi WJ, Xu M, Pang L, Liu ZY, Zhang W, Majeed S, Xu GB. Chem Eur J, 2014, 20: 4829–4835CrossRef
  10 a).Kwok RK, Leung CT,Lam JY, Tang BZ. Chem Soc Rev, 2015, 44: 4228–4238CrossRef
  b).Liang J, Tang BZ, Liu B. Chem Soc Rev, 2015, 44: 2798–2811CrossRef
  11.Minami T, Liu YL, Akdeniz A, Koutnik P, Esipenko NA, Nishiyabu R, Kubo Y, Anzenbacher P Jr. J Am Chem Soc, 2014, 136: 11396–11401CrossRef
  12.Megley CM, Dickson LA, Maddalo SL, Chandler GJ, Zimmer M. J Phys Chem B, 2009, 113: 302–308CrossRef
  13 a).Freeman R, Finder T, Bahshi L, Gill R, Willner I. Adv Mater, 2012, 24: 6416–6421CrossRef
  b).Sabherwal P, Shorie M, Pathania P, Chaudhary S, Bhasin KK, Bhalla V, Suri CR. Anal Chem, 2014, 86: 7200–7204CrossRef
  
• 作者单位：Chen Wang (1)
  Heng Zhang (3)
  Li Tian (1)
  Wei Zhu (1)
  Yue Lan (1)
  Jian Li (1)
  Hui Wang (1)
  Guanxin Zhang (2)
  Deqing Zhang (2)
  Shiling Yuan (3)
  Guangtao Li (1)
  
  1. Department of Chemistry, Tsinghua University, Beijing, 100084, China
  3. Department of Chemical Engineering, Shandong University, Jinan, 250100, China
  2. Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Chinese Library of Science
  Chemistry
  
• 出版者：Science China Press, co-published with Springer
• ISSN：1869-1870

文摘

The broad class of explosives includes nitro aromatics as well as challenging aliphatic nitro-organics whose detection is important from counter-terrorism and national security perspectives. Here we report a turn-on fluorescent sensor array based on aggregation-induced emission (AIE) fluorophores as receptors. To achieve a good sensing system with fast response, good sensitivity and low detection limit, three receptors with abundant chemical diversities for target analytes were synthesized. The turn-on response of the individual receptor showed highly variable and cross-reactive analyte-dependent changes in fluorescence. The excellent ability to identify a variety of explosives, especially the challenging aliphatic nitro-organics (2,3-dimethyl-2,3-dinitrobutane (DMNB), 1,3,5-trinitro-1,3,5-triazinane (RDX), cyclotetramethylene tetranitramine (HMX) and entaerythritol tetranitrate (PETN)), was demonstrated in qualitative and quantitative analyses with 100% accuracy. The fluorescence signal amplification in the presence of explosives allows for application of these receptors in a sensor microarray suitable for high-throughput screening. These results suggested that the cross-reactive sensor array based on AIE fluorophores could find a wide range of applications for sensing various analytes or complex mixtures.