Use of 11C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas

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• 作者：Norbert Galldiks ; Lutz W. Kracht ; Lothar Burghaus ; Anne Thomas ; Andreas H. Jacobs ; Wolf–Dieter Heiss and Karl Herholz
• 关键词：[11C]methionine PET ; Temozolomide ; Metabolic effects ; Malignant recurrent glioma ; Molecular imaging
• 刊名：European Journal of Nuclear Medicine and Molecular Imaging
• 出版年：2006
• 出版时间：May 2006
• 年：2006
• 卷：33
• 期：5
• 页码：516-524
• 全文大小：440 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Nuclear Medicine
  Imaging and Radiology
  Orthopedics
  Cardiology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1619-7089

文摘

Purpose The purpose of this study was to monitor the metabolic effects of temozolomide (TMZ) chemotherapy in malignant gliomas by means of repeated positron emission tomography (PET) with [11C]methionine (MET).