Pick reproducing kernel Hilbert spaces. In particular, we exhibit uncountably many discs in the ball of \(\ell ^2\) which are multiplier biholomorphic but have non-isomorphic multiplier algebras. We also show that there are closed discs in the ball of \(\ell ^2\) which are varieties, and examine their multiplier algebras. In finite balls, we provide a counterpoint to a result of Alpay, Putinar and Vinnikov by providing a proper rational biholomorphism of the disc onto a variety \(V\) in \({\mathbb {B}}_2\) such that the multiplier algebra is not all of \(H^\infty (V)\) . We also show that the transversality property, which is one of their hypotheses, is a consequence of the smoothness that they require." />