Overexpression of Zm-HINT1 in Arabidopsis thaliana enhances resistance to Fusarium graminearum

详细信息    查看全文

• 作者：Liuji Wu (1) (2)
  Huimin Zhang (1) (2)
  Jun Zhang (1) (2)
  Liancheng Wu (1) (2)
  Zhangying Xi (1) (2)
  Yanhui Chen (1) (2)
  
  1. Henan Agricultural University and Synergetic Innovation Center of Henan Grain Crops ; 63 Nongye Road ; Zhengzhou ; 450002 ; People鈥檚 Republic of China
  2. Key Laboratory of Physiological Ecology and Genetic Improvement of Food Crops in Henan Province ; Zhengzhou ; 450002 ; China
  
• 关键词：Histidine triad nucleotide binding protein 1(HINT1) ; Maize ; Subcellular localization ; Real ; time PCR ; Defense response ; Crop breeding
• 刊名：Plant Cell, Tissue and Organ Culture
• 出版年：2015
• 出版时间：May 2015
• 年：2015
• 卷：121
• 期：2
• 页码：511-518
• 全文大小：605 KB
• 参考文献：1. Ahel, I, Rass, U, El-Khamisy, SF, Katyal, S, Clements, PM, McKinnon, PJ, Caldecott, KW, West, SC (2006) The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates. Nature 443: pp. 713-716 CrossRef
  2. Asano, T, Kimura, M, Nishiuchi, T (2012) The defense response in Arabidopsis thaliana against Fusarium sporotrichioides. Proteome Sci 10: pp. 61 CrossRef
  3. Barberini, S, Savona, M, Raffi, D, Leonardi, M, Pistelli, L, Stochmal, A, Vainstein, A, Pistelli, L, Ruffoni, B (2013) Molecular cloning of SoHPPR encoding a hydroxyphenylpyruvate reductase, and its expression in cell suspension cultures of Salvia officinalis. Plant Cell, Tissue Organ Cult 114: pp. 131-138 CrossRef
  4. Barbier, E, Wang, JB (2009) Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level. BMC Neurosci 10: pp. 132 CrossRef
  5. Barbier, E, Zapata, A, Oh, E, Liu, Q, Zhu, F, Undie, A, Shippenberg, T, Wang, JB (2007) Supersensitivity to amphetamine in protein kinase-C interacting protein/HINT1 knockout mice. Neuropsychopharmacology 32: pp. 1774-1782 CrossRef
  6. Bechtold, N, Pelletier, G (1998) In planta Agrobacterium-mediated transformation of adult Arabidopsis thaliana plants by vacuum infiltration. Methods Mol Biol 82: pp. 259-266
  7. Bennett, JW, Klich, M (2003) Mycotoxins. Clin Microbiol Rev 16: pp. 497-516 CrossRef
  8. Brenner, C, Garrison, P, Gilmour, J, Peisach, D, Ringe, D, Petsko, GA, Lowenstein, JM (1997) Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nat Struct Biol 4: pp. 231-238 CrossRef
  9. Doehlemann, G, Wahl, R, Horst, RJ, Voll, LM, Usadel, B, Poree, F, Stitt, M, Pons-K眉hnemann, J, Sonnewald, U, Kahmann, R, K盲mper, J (2008) Reprogramming a maize plant: transcriptional and metabolic changes induced by the fungal biotroph Ustilago maydis. Plant J 56: pp. 181-195 CrossRef
  10. Erb, M, Flors, V, Karlen, D, Lange, E, Planchamp, C, D鈥橝lessandro, M, Turlings, TC, Ton, J (2009) Signal signature of aboveground-induced resistance upon belowground herbivory in maize. Plant J 59: pp. 292-302 CrossRef
  11. Fritig, B, Kauffmann, S, Dumas, B, Geoffroy, P, Kopp, M, Legrand, M (2007) Mechanism of the hypersensitivity reaction of plants. Wiley, New York
  12. Gong, Z, Morales-Ruiz, T, Ariza, RR, Rold谩n-Arjona, T, David, L, Zhu, JK (2002) ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase. Cell 111: pp. 803-814 CrossRef
  13. Goswami, RS, Kistler, HC (2004) Heading for disaster: Fusarium graminearum. Mol Plant Pathol 5: pp. 515-525 CrossRef
  14. Huffaker, A, Dafoe, NJ, Schmelz, EA (2011) ZmPep1, an ortholog of Arabidopsis elicitor peptide, regulates maize innate immunity and enhances disease resistance. Plant Physiol 155: pp. 1325-1338 CrossRef
  15. Klein, MG, Yao, Y, Slosberg, ED, Lima, CD, Doki, Y, Weinstein, IB (1998) Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp Cell Res 244: pp. 26-32 CrossRef
  16. Korsisaari, N, Rossi, DJ, Luukko, K, Huebner, K, Henkemeyer, M, Makela, TP (2003) The histidine triad protein HINT is not required for murine development or Cdk7 function. Mol Cell Biol 23: pp. 3929-3935 CrossRef
  17. Li, H, Zhang, Y, Su, T, Santella, RM, Weinstein, IB (2006) HINT1 is a haplo-insufficient tumor suppressor in mice. Oncogene 25: pp. 713-721 CrossRef
  18. Liu, Q, Puche, AC, Wang, JB (2008) Distribution and expression of protein kinase C interactive protein (PKCI/HINT1) in mouse central nervous system (CNS). Neurochem Res 33: pp. 1263-1276 CrossRef
  19. Luo, X, Bai, X, Sun, XL, Zhu, D, Liu, BH, Ji, W, Cai, H, Cao, L, Wu, J, Hu, M, Liu, X, Tang, LL, Zhu, YM (2013) Expression of wild soybean WRKY20 in Arabidopsis enhances drought tolerance and regulates ABA signaling. J Exp Bot 64: pp. 2155-2169 CrossRef
  20. Mika, A, L眉thje, S (2003) Properties of guaiacol peroxidase activities isolated from corn root plasma membranes. Plant Physiol 132: pp. 1489-1498 CrossRef
  21. Ryals, J, Lawton, KA, Delaney, TP, Friedrich, L, Kessmann, H, Neuenschwander, U, Uknes, S, Vernooij, B, Weymann, K (1995) Signal transduction in systemic acquired resistance. Proc Natl Acad Sci USA 92: pp. 4202-4205 CrossRef
  22. Strable, J, Scanlon, MJ (2009) Maize (Zea mays): a model organism for basic and applied research in plant biology. Cold Spring Harb Protoc.
  23. Su, T, Suzui, M, Wang, L, Lin, CS, Xing, WQ, Weinstein, IB (2003) Deletion of histidine triad nucleotide-binding protein 1/PKCinteracting protein in mice enhances cell growth and carcinogenesis. Proc Natl Acad Sci USA 100: pp. 7824-7829 CrossRef
  24. Urban, M, Daniels, S, Mott, E, Hammond-Kosack, K (2002) Arabidopsis is susceptible to the cereal ear blight fungal pathogens Fusarium graminearum and Fusarium culmorum. Plant J 32: pp. 961-973 CrossRef
  25. Loon, LC, Strien, EA (1999) The families of pathogenesis-related proteins, their activities, and comparative analysis of PR-1 type proteins. Physiol Mol Plant Pathol 55: pp. 85-97 CrossRef
  26. Varadarajulu, J, Lebar, M, Krishnamoorthy, G, Habelt, S, Lu, J, Bernard Weinstein, I, Li, H, Holsboer, F, Turck, CW, Touma, C (2011) Increased anxiety-related behaviour in HINT1 knockout mice. Behav Brain Res 220: pp. 305-311 CrossRef
  27. Varadarajulu, J, Schmitt, A, Falkai, P, Alsaif, M, Turck, CW, Martins-de-Souza, D (2012) Differential expression of HINT1 in schizophrenia brain tissue. Eur Arch Psychiatry Clin Neurosci 262: pp. 167-172 CrossRef
  28. Vianello, A, Zancani, M, Nagy, G, Macri, F (1997) Guaiacol peroxidase associated to soybean root plasma membranes oxidizes ascorbate. J Plant Physiol 150: pp. 573-577 CrossRef
  29. Vyroubalov谩, S, V谩clav铆kov谩, K, Tureckov谩, V, Nov谩k, O, 拧mehilov谩, M, Hluska, T, Ohnoutkov谩, L, Fr茅bort, I, Galuszka, P (2009) Characterization of new maize genes putatively involved in cytokinin metabolism and their expression during osmotic stress in relation to cytokinin levels. Plant Physiol 151: pp. 433-447 CrossRef
  30. Wang, L, Zhang, Y, Li, H, Xu, Z, Santella, RM, Weinstein, IB (2007) HINT1 inhibits growth and activator protein-1 activity in human colon cancer cells. Cancer Res 67: pp. 4700-4708 CrossRef
  31. Weiske, J, Huber, O (2006) The histidine triad protein HINT1 triggers apoptosis independent of its enzymatic activity. J Biol Chem 281: pp. 27356-27366 CrossRef
  32. Weitzdoerfer, R, Stolzlechner, D, Dierssen, M, Ferreres, J, Fountoulakis, M, Lubec, G (2001) Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal down syndrome brain. J Neural Transm Suppl 61: pp. 347-359
  33. Wu, LJ, Wang, XT, Wu, LC, Wang, PA, Chen, YH (2011) Molecular cloning and expression analysis of an HINT1 homologue from maize (Zea mays L.). Plant Mol Biol Rep 29: pp. 1006-1012 CrossRef
  34. Wu, LJ, Hu, XL, Chen, X, Wu, LC, Chen, YH (2014) Identification and characterization of an E3 ubiquitin ligase Rbx1 in maize (Zea mays L.). Plant Cell, Tissue Organ Cult 116: pp. 253-260 CrossRef
  35. Yang, JW, Yu, SH, Ryu, CM (2009) Priming of defence-related genes confers root-colonizing bacilli-elicited induced systemic resistance in pepper. Plant Pathol J 25: pp. 303-440 CrossRef
  36. Zhang, X, Henriques, R, Lin, SS, Niu, QW, Chua, NH (2006) Agrobacterium-mediated transformation of Arabidopsis thaliana using the floral dip method. Nat Protoc 1: pp. 641-646 CrossRef
  37. Zhang, YJ, Li, H, Wu, HC, Shen, J, Wang, L, Yu, MW, Lee, PH, Weinstein, IB, Santella, RM (2009) Silencing of HINT1, a novel tumor suppressor gene, by promoter hypermethylation in hepa-tocellular carcinoma. Cancer Lett 275: pp. 277-284 CrossRef
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Plant Sciences
  Plant Physiology
  
• 出版者：Springer Netherlands
• ISSN：1573-5044

文摘

Histidine triad nucleotide binding protein 1(HINT1) plays an important role in many biological processes especially in cell biology, and they have been found in a wide variety of species. However, the functional attributes of HINT1 homologues in plants have not yet been reported. We have previously isolated the full-length cDNA of an HINT1 homologue from maize (Zea mays L.), designated as Zm-HINT1. Subcellular localization was analysed after particle-mediated transient transformation of onion epidermal cells. The result revealed that Zm-HINT1 was targeted to the nucleus. Based on real-time PCR analysis, the expression level of Zm-HINT1 increased significantly after salicylic acid or jasmonic acid treatments. To further investigate the potential physiological role of Zm-HINT1, a binary vector was constructed for Zm-HINT1 synthesis and transgenic Arabidopsis lines were generated by Agrobacterium-mediated transformation. Transgenic Zm-HINT1 plants showed increased resistance to Fusarium graminearum compared to the wild type and control plants. Futhermore, real-time PCR results revealed that the pathogen defense genes pathogenesis-related 4 (PR-4) and a peroxidase were upregulated by Zm-HINT1 overexpression. Thus, our data demonstrated that Zm-HINT1 induced antifungal activity against Fusarium graminearum and it may be useful for crop breeding in improving biotic stress tolerance.